Adverse drug reactions with an immunological basis (ADRIB) may involve activation of other concomitant, non-specific mechanisms, amplifying the specific response and contributing to the severity and duration. One concomitant mechanism could be the generation of reactive oxygen species (ROS) and/or their detoxification by anti-oxidants, including anti-oxidant enzymes. We analysed the activity of...

background: reactive oxygen species (ros)-induced lipidperoxidation can lead to dysfunction of sperm and thereby, infertility may be occurred. so, always there is a balance between amount of ros and anti-oxidant molecules in semen. anti-oxidant enzymes of sperm; superoxide dismutase (sod), glutathione peroxidase (gpx), catalse and zinc and selenium can protect it from destructive effects of ros...

1. Diabetic neuropathy is one of the most common complications of diabetes and oxidative stress has been implicated to play a major role in its pathophysiology. 2. In the present study, we targeted oxidative stress using trolox, an anti-oxidant, in streptozotocin-induced diabetic neuropathy in rats. 3. Compared with control rats, diabetic rats showed significant deficits in motor nerve conducti...

BACKGROUND Despite the widespread use of roots of Cassia sieberiana in managing several health conditions including gastric ulcer disease, there is little scientific data to support the rational phytotherapeutics as an anti-ulcer agent. This paper reports an evaluation of the in vivo anti-oxidant properties of an aqueous root bark extract of C. sieberiana in experimental gastric ulcer rats in a...

introduction: shallot is a plant which belongs to alium and albale family , this is a native plant from iran which is self – grown in high zones. by regard to further use of medicine and plant’s product , use of herbal plants has on important nole in medical treatment and preventi of diseale. the purpose of this study is the photo chemistry properties and anti – bacterial effects of this plant....

background: artemisia species with common persian name of dermaneh are found all over iran and are used for treatment in infectious diseases such as malaria, hepatitis and other diseases. some artemisia species are used in traditionally as tonic and anti-helmintic in north of iran. objective: the aim of this study was to investigate chemical composition of the essential oil of artemisia hausskn...

luteolin is a flavone in medicinal plants as well as some vegetables and spices. it is a natural anti-oxidant with less pro-oxidant potential but apparently with a better safety profile. the purpose of this study was to investigate the molecular mechanism of luteolin-mediated apoptosis of mg-63 human osteosarcoma cells. mtt assay kit was employed to evaluate the effects of luteolin on mg-63 cel...

objective(s): methylsulfonylmethane (msm) is a sulfur-containing compound found in a wide range of human foods including fruits, vegetables, grains and beverages. in this study the effect of msm pretreatment on acetaminophen induced liver damage was investigated. materials and methods: male sprague dawley rats were pretreated with 100 mg/kg msm for one week. on day seven rats were received acet...