background: there is much evidence indicating that natural substances from edible and medicinal plants possess powerful antioxidant and hepatoprotective activities. the objective of the present study was to investigate the potential hepatoprotective effect of silymarin in fish exposed to malathion. methods: zebra cichlid fish were allocated into five groups of which one group received normal fe...

introduction: recently depleted uranium is being widely used as anti-armour ammunition and at very high temperature, results in information of an aerosol of very small uranium oxide particles, which may be inhaled. it is alleged that these particles represent a new battlefield hazard because of the chemical toxicology and/or radioactivity. method & materials: male wistar strain albino rats were...

background: the early stage of copper poisoning is difficult to be clinically diagnosed in sheep and has not been documented clearly yet. objectives: to assess biomarkers in predicting early copper poisoning in sheep, blood samples were collected from several groups of animals from a naturally copper poisoning occurrence in an industrial region. methods: animals were divided into four experimen...

background: cyclosporine a (csa) is a potent immunosuppressant drug with therapeutic and toxic actions. the use of csa is limited by its toxicity. several researchers had proposed that oxidative stress could play an important role in csa-induced toxicity. arbutin has recently been shown to possess antioxidative and free radical scavenging abilities.the present study was designed to investigate ...

background & aim: glycyrrhiza l. (fabaceae) consists of perennial herbs grow in sandy soils with hard lightness. three species of the genus grow in iran, among them g. glabra l. has the widest distribution. it is well known in english as licorice and the root extract includes flavonoids and glycyrrhizin are used widely in medicine, food industry, tobacco products and other industries. liqui...

nitric oxide (no) is a highly reactive signaling molecule and plays a variety of physiological roles in plants. the research on the application of no to postharvest preservation of flowers and fruits shows great promise in recent years. however, the physiological mechanism of exogenous no to affect cut flowers is not very clear, and no donor treatment protected plants from damage by increasing ...

anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet ccl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). group i (control), while group ii was given ccl4 (3 ml /kg/day, ip). animals of groups iii received only propofol (10 mg/kg/day, ip). group iv was given propofol+ ccl4. group v was admin...

Many diseases associated with ageing have an underlying oxidative stress and accompanying inflammatory component, for example, Alzheimer’s disease or atherosclerosis. Reviewed in this manuscript are: the role of oxidative stress in activating the transcription factor nuclear factor kappa B (NFκB), the role of NFκB in activating proinflammatory gene transcription, strong oxidants produced by cel...