'Krishna Jeerakam' is a small black seed which is used in the preparation of certain Ayurvedic medicines. The terms 'Karavi', 'Prithvi' and 'Kala' are used frequently as its synonyms. Each word conveys a specific meaning which indicates one or other property of the drug. 'Karavi' means savior from the fear of death and 'prithvi' conveys the meaning 'famous' and kala emphasizes the black colour ...

The synthesis and spectroscopic characterization of new axially ligated indium(III) porphyrin complexes were reported. Chloroindium(III) porphyrin (TPPIn-Cl) was obtained in good yield by treating the corresponding free base with indium trichloride. The action of the different phenols on chloroderivatives (TPPIn-Cl) led to the corresponding phenolato complexes (TPPIn-X). These derivatives were ...

Podophyllum hexandrum Royle syn P. emodi Wall. ex Hook.f. & Thoms. is an endangered and valuable medicinal plant, distributed in the Himalayan zone at an altitudes ranging from 2000 to 4000 m above MSL. It is an herbaceous and rhizomatous perennial plant also found in few pockets of Indian cold desert (Ladakh and Lahaul-Spiti). Its rhizomes and roots contain about 8% of podophylloresin from whi...

l glutaminase, a therapeutic enzyme obtained from marine actinomycetes gains importance because of their adaptability to varied environmental factors. an experimental study was carried out to isolate the l glutaminase producing actinomycetes from the marine sediment of thoothukudi. marine sediment sample was collected from six different locations of the thoothukudi coastal ecosystem, enriched w...

Background: Cancer refers to the abnormal growth of cells and is still the most common cause of morbidity in world. The purpose of this study was to determine cytotoxicity effect of high molecular weight (HMWC) and low molecular weight of chitosan (LMWC) on three cancerous cell lines MCF-7, HeLa and Saos-2 with different histological origin. Methods: The anticancer property of two types of chi...

Tumor hypoxia is causally related with resistance to adriamycin (ADR), and hyperbaric oxygen therapy has been shown to enhance the chemotherapeutic effect of the drug. It is believed that exposure to oxygen leads to an increase of intracellular reactive oxygen species (ROS) concentration. To monitor ROS involvement in this improved anticancerous effect, we used a new method of ROS detection bas...

Phyllanthus amarus (PA) is a small herb indigenous to Amazon Basin .It is well known for its medicinal properties and widely used by oriental countries. It is reported to contain lignans,alkaloids,flavonoids,galloatnoids ,glycosides and alkaloids. It possesses antiviral, antiparasitic, antimalarial, antimicrobial, anticancerous, anti-diabetic and anti-Cholesterol agents. It acts on kidney stone...

OBJECTIVES There have been developed to use targeting ability for antimicrobial, anticancerous, gene therapy and cosmetics through analysis of various membrane proteins isolated from cell organelles. METHODS It was examined about the lysosomal membrane protein extracted from lysosome isolated from HeLa cell treated by 100 ppm melanin for 24 hours in order to find associated with targeting abi...