AIM OF THE STUDY To document the ethnobotanical knowledge on antidiarrhoeal plant use by lay people in a rural community in northern Maputaland. MATERIALS AND METHODS Interviews were conducted amongst homestead inhabitants, using structured questionnaires. The focus was on the medicinal plants which are growing in and around the immediate vicinity of the homesteads. RESULTS Twenty-three pla...

The alkaloids from the ethanolic extract of H. antidysenterica seeds were evaluated for their antibacterial activity against clinical isolates of enteropathogenic Escherichia coli (EPEC) in vitro, and their antidiarrhoeal activity on castor oil-induced diarrhoea in rats, in vivo. The plasmid DNA, whole cell lysate and outer membrane protein profile of a clinical isolate of EPEC was determined i...

dracocephalum kotschyi boiss, a member of labiatae family, is a native plant to iran, which has been reported to have immunomodulatory, antihyperlipidemic and antispasmodic activities. the objective of this research was to study the antispasmodic and antidiarrhoeal activities of hydroalcoholic and hexane extracts of d. kotschyi in mice. furthermore, the antidiarrhoeal and antispasmodic effect o...

The antidiarrhoeal activity of Cryptocoryne spiralis rhizomes extract (250, 500, 750 mg/kg, po) was evaluated using faecal excretion, castor oil-induced diarrhoea, small intestinal transit, intestinal fluid accumulation, gastric emptying and PGE2 induced enteropooling models in rats. In addition, various biochemical estimations, histopathological studies and antibacterial evaluations on strains...

Diarrhoeal diseases due to enterotoxigenic Escherichia coli continue to be a cause of global concern. Medicinal plants have been gaining popularity as promising antidiarrhoeal agents. In the present study, four antidiarrhoeal plants, viz. Aegle marmelos, Cyperus rotundus, Psidium guajava and Zingiber officinale were screened against a heat-stable toxin-producing enterotoxigenic E. coli strain. ...

The selected plant Alternenthera sessilis (L.), Houttuynia cordata (Thunb) Murraya koenigii (L.) and Ziziphus oenoplia (L) Miller has been used traditionally in Assam, India for the treatment of diarrhoea and dysentery. However, the claims need to be validated by a suitable experimental model. Therefore, the present study was under taken to evaluate the effect of 50% methanol extracts of Altern...

This study screened the antidiarrhoeal, antimicrobial and cytotoxic effects of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). The extract was tested against castor oil-induced diarrhoea in a model of albino rats and showed significant antidiarrhoeal activity (P<0.01). Disc diffusion technique was used to test the in vitro antibacterial activities of the extract and exhibited ...

Two hundred and ninety five children admitted with acute gastroenteritis from January 1, 1996 to December 31, 1996 to the Paediatric unit, University of Malaya Medical Centre, Kuala Lumpur, were reviewed. Eighty-nine percent of children received treatment before admission. Information regarding the type of treatment received were available in 152 (52%) cases. Eighty percent of them were prescri...

This study describes the antidiarrhoeal and bronchodilatory activities of Valeriana wallichii D.C. (Valerianaceae). The crude extract of V. wallichii (Vw.Cr) caused inhibition of castor oil-induced diarrhoea in mice at 300-600 mg kg⁻¹. In guinea-pig trachea, Vw.Cr concentration dependently (0.03-3.0 mg mL⁻¹) relaxed the low K+ (25 mM)-induced contractions, with a mild effect on the contractions...