نتایج جستجو برای: antihelmintic
تعداد نتایج: 116 فیلتر نتایج به سال:
The development of anthelmintic resistance in sheep gastrointestinal nematodes to commercial anthelmintics has led enormous economic losses many parts the world. For this reason, new sustainable strategies for control these parasites are being actively searched, which include use different alternatives such as plant essential oils. aim study was determine chemical composition oil coriander (Cor...
The first synthesis of a naturally occurring tetrapeptide cyclo-(isoleucyl-prolyl-leucyl-alanyl) has been achieved using a solution-phase technique via coupling of dipeptide segments Boc-L-Pro-L-Leu-OH and L-Ala-L-Ile-OMe. Deprotection of the linear tetrapeptide unit and its subsequent cyclization gave a cyclopeptide, identical in all aspects to the naturally occurring compound. Bioactivity res...
Calotropis procera is a small, erect plant, which is used in several traditional medicines to treat many diseases. It is a native of most of the Asian and African countries. All plant parts exude thick white milky juice (latex) on cut or break. This shrub has been known to possess analgesic, antitumor, antihelmintic, antioxidant, hepatoprotective, antidiarrhoeal, anticonvulsant, antimi...
New drugs active against drug-resistant tuberculosis are urgently needed to extend the range of TB treatment options to cover drug resistant infections. Quinoxaline derivatives show very interesting biological properties (antibacterial, antiviral, anticancer, antifungal, antihelmintic, insecticidal) and evaluation of their medicinal chemistry is still in progress. In this review we report the p...
The in vitro antifungal activity of albendazole, a benzimidazole widely used as an antihelmintic drug in humans, was investigated and assessed for its activity against Aspergillus spp. Forty-eight isolates, representing the most frequent species found in human pathology [Aspergillus fumigatus (n = 27), Aspergillus flavus (n = 10), Aspergillus terreus (n = 7), Aspergillus nidulans (n = 3) and As...
Centratherum anthelminticum commonly known as ‘black cumin’, a traditional Ayurvedic medicine, has been used for centuries for curing common ailments such as fever, cough, and diarrhoea, and its is also used as a general tonic. A wide range of secondary metabolites such as: aliphatic fatty acids, flavones, saponins, steroids and glycosides have been reported from the C. anthelminticum. Its extr...
PURPOSE Levamisole is an antihelmintic and immunomodulator used as a dewormer and in combination with other forms of chemotherapy to treat colon cancer, melanoma, and head and neck cancer. It has also been used for treating dermatologic disorders such as verrucae. However, its benefits remain controversial and serious side effects such as central nervous system toxicity are unexpected. CASE R...
WNT signaling plays a key role in the self-renewal of tumor initiation cells (TICs). In this study, we used pyrvinium pamoate (PP), an FDA-approved antihelmintic drug that inhibits WNT signaling, to test whether pharmacologic inhibition of WNT signaling can specifically target TICs of aggressive breast cancer cells. SUM-149, an inflammatory breast cancer cell line, and SUM-159, a metaplastic ba...
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