New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamide derivatives and a wide range of coumarins. The structures of the obtained compounds were elucidated by IR and NMR spectra and also analytical elemental analysis. In the next step, the above mention...

new sulfonamide and amide derivatives containing coumarin moieties; oxo-2h-chromen-sulfamoylphenylacetamides and oxo-2h-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamide derivatives and a wide range of coumarins. the structures of the obtained compounds were elucidated by ir and nmr spectra and also analytical elemental analysis. in the next step, the above mention...

Chemical investigation of Garcinia eugenifolia and Calophyllum enervosum yielded six compounds. One of these was found to be a novel compound identified as enervosanone. Five known compounds cambogin, epicatechin, osajaxanthone, rubraxanthone and isocowanol, were also isolated. These compounds were tested for their bioactivity as antimicrobial, antioxidant and cytotoxicagents. Antimicrobial...

We explored the potential of poly(oxonorbornene)-based synthetic mimics of antimicrobial peptides (SMAMPs), a promising new class of antimicrobial polymers with cell-selectivity and low resistance development potential, for clinical applications. We evaluated their antimicrobial activity against a panel of seven clinical and regulatory relevant bacteria strains, and tested their toxicity with t...

This study evaluated the antimicrobial, antioxidant and toxicity activity of essential oils (EOs) Hymenaea courbaril L. var. bark Syzygium cumini (L.) Skeels leaves. The EOs were extracted by hydrodistillation chemically characterized gas chromatography coupled to mass spectrometry (GC/MS). ABTS DPPH assay used evaluate activity. For assay, lethality was against Artemia salina Leach. antimicrob...

background: bacteremia due to enterococcus faecalis is usually caused by strains resistant to most antibiotics. effective management of the disease is dependent on rapid detection and characterization of the bacteria, and determination its sensitivity pattern to antimicrobial drugs. the aim of this study was to investigate a more rapid and reliable assay for simultaneous diagnosis of enterococc...

chemical investigation of garcinia eugenifolia and calophyllum enervosum yielded six compounds. one of these was found to be a novel compound identified as enervosanone. five known compounds cambogin, epicatechin, osajaxanthone, rubraxanthone and isocowanol, were also isolated. these compounds were tested for their bioactivity as antimicrobial, antioxidant and cytotoxicagents. antimicrobial ass...

The antioxidant, antimicrobial and anticancer activity of n-hexane extract Mollugo nudicaulis Lam. is interest. antioxidant the was determined by separate methods radical scavenging assays. Antimicrobial analyzed disc diffusion method on fungi species, gram positive negative species. potential plant evaluated A2780 cell lines MTT assay. Results exposed that, M.nudicaulis possess comparable sign...

regarding increasing rate of drug resistance among microbial pathogens, a global search to find new antimicrobial agents from natural compounds with fewer side effects has been considered by many researchers worldwide. bioactive compounds with good antimicrobial activity have been isolated from different algae and cyanobacteria. the current study was performed to determine antimicrobial potenti...