Alternative treatment methods for pathogens and microbial biofilms are required due to the widespread rise in antibiotic resistance. Antimicrobial photodynamic therapy (aPDT) has recently gained attention as a novel method to eradicate pathogens. The aim of this study was to evaluate the antimicrobial effects of a novel aPDT method using visible light (vis) and water infiltrated infrared A (wIR...

Antimicrobial photodynamic therapy (aPDT) was demonstrated to be effective against various species of Gram-positive bacteria. However, the complex structure a Gram-negative bacteria envelope limits application aPDT. Thus, goal this study improve efficiency antimicrobial with Fotoditazin uropathogenic The non-ionic detergent Triton X-100 and emulsifier Tween 80 were tested. effect extracellular ...

objectives: dental caries and periodontal diseases are caused by infection of teeth and supporting tissues due to complex aggregate of bacteria known as biofilm, firstly colonized by streptococci. the main purpose of this in vitro study was to evaluate the antimicrobial effects of toluidine blue o (tbo) and radachlorin® in combination with a diode laser on the viability of streptococcus mutans....

Introduction: Due to penetration of pathogenic bacteria into the periodontal tissues in moderate to severe periodontitis, the mechanical methods are not sufficient in these cases. Therefore, administration of local/systemic antibiotic is recommended following mechanical root debridement. However, side effects of antibiotics such as microbial resistance and patient allergy led to development of ...

Curcumin (CUR) has been used as photosensitizer in antimicrobial Photodynamic Therapy (aPDT). However its poor water solubility, instability, and scarce bioavalibility hinder its in vivo application. The aim of this study was to synthesize curcumin in polymeric nanoparticles (NP) and to evaluate their antimicrobial photodynamic effect and cytoxicity. CUR in anionic and cationic NP was synthesiz...

introduction: due to penetration of pathogenic bacteria into the periodontal tissues in moderate to severe periodontitis, the mechanical methods are not sufficient in these cases. therefore, administration of local/systemic antibiotic is recommended following mechanical root debridement. however, side effects of antibiotics such as microbial resistance and patient allergy led to development of ...

Antibiotic treatments frequently fail due to the development of antibiotic resistance, underscoring the need for new treatment strategies. Antimicrobial photodynamic therapy (aPDT) could constitute an alternative therapy. In bacterial suspensions of Staphylococcus aureus, which is commonly implicated in cutaneous and mucosal infections, we evaluated the in vitro efficacy of aPDT, using the phot...

OBJECTIVE The aim of this study was to assess the bactericidal efficacy of antimicrobial photodynamic dynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) against periodontal pathogens. BACKGROUND DATA SRP followed by laser therapy has better clinical outcomes than conventional SRP alone. MATERIALS AND METHODS The question addressed was "Does aPDT as an adjunct to SRP exhi...

Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial photodynamic therapy (aPDT), also called photodynamic inactivation, is emerging as a promising alternative to treatments based on conventional antibiotics. We have explored the effectiveness of me...

The aim of the present study was to compare effects phenothiazine photosensitizers methylene blue (MB), toluidine blue-O (TBO) and butyl (BuTB) in antimicrobial photodynamic therapy (aPDT), as adjuvant scaling root planing (SRP) treatment experimental periodontitis (EP) rats. 120 Wistar rats underwent ligation around lower left molar. After seven days, ligature removed. animals were separated i...