Regional chemotherapy is an attractive but underevaluated method of treating locally advanced breast cancer. We have combined two novel methods of targeting by delivering a single pulse of adriamycin-loaded albumin microspheres down a radiologically placed internal mammary artery catheter. A complete response was observed and prolonged local control achieved.

The anticancer effects of photodynamic hyperthermal chemotherapy (PHCT), which consists of a combination of indocyanine green photodynamic hyperthermal therapy and local chemotherapy, have previously been reported. The present study investigated the effect of PHCT in six cases of feline vaccine-associated sarcoma (FVAS) following conservative surgical resection. No recurrence was observed in th...

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Exposure of health care workers to antineoplastic drugs and subsequent adverse health effects is still an open issue. Very little has been studied on the extent of occupational exposure and handling conditions of antineoplastic drugs in Iran. We aimed to determine cyclophosphamide and ifosfamide concentrations in the urine samples of oncology healthcare workers. In addition, we assessed workpla...

Objectives Cancer is a world public health problem, and the incidence in children increase 1% per year. Despite its high efficacy, antineoplastic therapy induces effects of significant toxicity, often causing patient hospitalization, difficulties continuing oncotherapy or noncontinuation adequate treatment for nonprogression disease. Oral mucositis one most common deleterious effects; it causes...

Preoperative radiotherapy is standard procedure in rectal cancer treatment protocols. Experience and analysis of clinical and laboratory features of the results of this procedure have established that the response to radiotherapy, in order to reduce the volume of tumor and adenopathies of stations I and II is highly variable, from complete disappearance of the tumor mass, to the lack of respons...

Dental treatment of patients with leukemia should be planned on the basis of antineoplastic therapy which can be chemotherapy with or without radiotherapy and bone marrow transplantation. Many are the oral manifestations presented by these patients, arising from leukemia and/or treatment. In addition, performing dental procedures at different stages of treatment (before, during, or after) must ...

a cross-sectional study to determine whether occupational exposure to antineoplastic drugs can cause hematologic changes was performed. blood samples were collected from a group of 24 hematology/oncology nurses who were exposed to antineoplastic drugs during a mean preiod of 5.5 years (standard error =1.1). the control group, matched by sex, and age, consisted of 18 nurses, worked on other sect...