Cyanobacteria contribute significantly to the maintenance of flooded rice field fertility. In this investigation, the protective effect of osmolytes and antioxidative enzymes was studied on the paddy field cyanobacterial biofertilizer; Anabaena variabilis exposed to Malathion pesticide. With increasing concentration of malathion the test organism showed increased free radical mediated toxicity....

Since skin is the first barrier separating the body from the external environment, impaired wound healing can be life threatening to living organisms. Delayed healing processes are observed in animals under certain circumstances, such as advanced age, diabetes, and immunosuppression, but the underlying mechanisms of the abnormality remain elusive. Redox homeostasis is defined as the balance bet...

To understand the adaptive mechanisms, and the strategy and direction of evolution of exploiting plants for living in oasis-desert transitional areas where there was a water gradient, mechanisms of C4 photosynthesis and antioxidative protection were studied in leaves and assimilating shoots of C3 desert shrub Hedysarum scoparium under water gradient accompanied with high irradiance and high tem...

Desert plants are exposed to a combination of environmental stress conditions, including water deficit, high temperature and high irradiance. We focused on antioxidative protection systems of C4 desert plant Haloxylon ammodendron and C3 desert plant Hedysarum scoparium within arid dune ecosystem with artificial controlling water availability. The activities of antioxidative enzymes (SOD, POD an...

BACKGROUND/AIM Chronic echinococcocal disease is the parasite human disease caused by the penetration of larval (asexual) stages of the canine tapeworm (Echinococcus granulosus) in the liver of humans. After the penetration of the parasite, the host organism react by activating complement-depending immune response. The aim of this study was to elucidate the influence of larval form of Echinococ...

The leaf of Solanum anomalum used in ethnomedicine for the treatment various ailments such as diabetes was evaluated antioxidative stress and hepatoprotective potentials against hepatic injuries alloxan-induced diabetic rats. Antioxidative activities extract fractions (70-210 mg/kg) were assessed by determining oxidative markers levels, liver function indices histopathological study livers trea...

AIMS Increased levels of reactive oxygen species cause oxidative stress and severely damage lipids, proteins, and DNA. We have previously shown that partial proteasome inhibition induces an antioxidative gene pattern in endothelial cells. Here, we elucidate the mechanisms of proteasome inhibitor-mediated upregulation of antioxidative enzymes and cytoprotection. METHODS AND RESULTS Non-toxic p...

Many insects in temperate regions overwinter in diapause, during which they are cold hardy. In these insects, one of the metabolic adaptations to the unfavorable environmental conditions is the synthesis of cryoprotectants/anhydroprotectants. The aim of this study was to investigate the connection between the antioxidative system and synthesis of cryoprotectants (mainly glycerol) in diapausing ...

Increased mesangial cell proliferation is a hallmark of many glomerulopathies in humans. Whereas the pathogenic role of reactive oxygen species (ROS) in the development of experimental mesangioproliferative glomerulonephritis (GN) is well established, very little is known about the mechanisms leading to increased ROS concentrations in the glomerulus. This study therefore examined glomerular ROS...

This work was done to clarify the relation between the changes of lipid peroxidation and the activities of antioxidative protective enzymes in lungs of rats exposed acutely, subacutely, and chronically to nitrogen dioxide. It was confirmed that the activities of the antioxidative enzymes to protect cells from oxidative stress increased in an early phase, and then the activities decreased gradua...