CONTEXT Rifampicin-based antitubercular therapy reduces the plasma concentrations of nevirapine and efavirenz. The virological consequences of these interactions are not well described. OBJECTIVE To assess the effectiveness and tolerability of concomitant efavirenz- or nevirapine-based combination antiretroviral therapy and rifampicin-based antitubercular therapy. DESIGN, SETTING, AND PARTI...

BCG therapy is used as a treatment in bladder cancer. Intravesical administration of Bacillus Calmette-Guérin is used as a treatment method in superficial bladder cancer. While it is commonly effective, some serious side effects may occur. We hereby report a 65-year-old man who developed granulomatous hepatitis as a complication following BCG therapy. He was treated successfully with antituberc...

Triazole is a five member heterocyclic nucleus has attracted a wide consideration in exploration for the new remedial agents. This nucleus acts very important role in biological fields for various biologically active molecules. The chemistry of triazole compounds has expected considerable interest due to their synthetic and effective biological properties likes analgesic, antinflammatory, antio...

The Revised National Tuberculosis Control Program (RNTCP) has initiated provision of antitubercular therapy for children with strategy of patient-wise boxes for the 4 different weight bands (6- 10 kg; 11- 17 kg; 18- 25 kg; 26- 30 kg). We evaluated the dose of individual drugs delivered by this approach to children of varying weights. The following areas of concern were identified: underdosing o...

We present a case of a 33-year-old woman who presented with phlyctenular conjunctivitis while on treatment for spinal intramedullary tuberculosis. She was treated with topical steroids along with continuation of antitubercular therapy, and improved on this treatment.

Pawan Kumar Mishra*, Jaya Dwivedi, Rajani Chauhan Department of Pharmacy, Vishveshwarya Group of Institutions, Dadri, Gautam Budh Nagar (U.P.), 203207. Department of Pharmaceutical Chemistry, Banasthali University, P.O. Banasthali Vidyapith (Rajasthan)-304022, India Department of Pharmacy, Banasthali University, P.O. Banasthali Vidyapith (Rajasthan)-304022, India *Corresponding author: pkmpharm...

Blood samples of animals from groups I and II were taken for liver function tests by cardiac puncture under ether anaesthesia Hepatotoxicity due to antitubercular drugs is found to be mediated through oxidative stress and free radical damage to hepatocytes (1, 2, 3). The antioxidants α-tocopherol and selenium are known exert beneficial effect in antitubercular drugs induced hepatotoxicity (4, 5...

We report the case of an immunocompetent patient with an isolated tuberculoma of the liver, which was diagnosed by percutaneous US-guided liver biopsy. The patient received an antitubercular therapy, and there has been no relapse to date.