BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic metabolic syndrome caused by insulin secretion abnormalities, action, or both. Gene polymorphism risk factor of T2DM. AIM: This study aims to see the role Apa-I Vitamin D receptor gene on METHODS: was an analytic observational with case–control approach, consisting 70 T2DM patients and healthy subjects as control. Genotyping performed usi...

AMA Gawish E, Abdelsameea Shaban Osheba I, Mohsen Y, El-Abd M. Epidermal growth factor rs4444903 polymorphism and risk of cholangiocarcinoma. A case control study. Clinical Experimental Hepatology. 2023;9(2):138-145. doi:10.5114/ceh.2023.128131. APA Gawish, E., Abdelsameea, Osheba, I., Mohsen, Y., & El-Abd, (2023). Hepatology, 9(2), 138-145. https://doi.org/10.5114/ceh.2023.128131 Chicago Eman ...

Apurinic acid (APA) obtained by mild acid hydrolysis of DNA was degraded to low-molecular-weight fragments. The fraction with an average molecular weight of 19,500 daltons reduced cell proliferation (L5178Y mouse lymphoma cells) on a molar basis more sensitively than did APA fractions of a lower molecular weight. Reduced cell proliferation was due to cytostatis rather than cytotoxicity. Cells t...

T he end of 10 years as Editor-in-Chief of Ambulatory Pediatrics provides me some perspective on the growth of the journal and the Academic Pediatric Association (APA) over this decade. During my time on the board of the APA (chair of the Public Policy Committee and the Research Committee at different times), I had reluctantly supported the notion that the APA should have an official journal, a...

Preface ........................................................................ Executive Summary and Recommendations Evaluation of Levels of Evidence .............................. Terminology .............................................................. Synopses of Literature Reviews and Opinions with Respect to Recommendations ................................. Why APA Recommendations Are N...

Vitamin D receptor (VDR) gene is recognized as candidate gene for susceptibility to Type 2 diabetes mellitus (T2DM). The goal of this study was to search the eventual association between VDR gene polymorphisms and T2DM in Moroccans patients. Materials and Methods: 176 patients with T2DM and 177 Healthy controls from the Moroccans population were recruited. Bsm-I(rs1544410), Fok-I(rs10735810) an...