Objective(s): Apolipoprotein E genotype (APOE) polymorphism affects lipid levels and coronary artery disease (CAD) risk. The aim of this study was to study the association of the Apolipoprotein E genotypes with coronary artery disease in the Iranian population.   Materials and Methods: The Apolipoprotein E genotype in DNA samples extracted from 66 CAD+ patients and 61 control s...

Previous researches have demonstrated associations between high obesity indices with increased risk of metabolic and cardiovascular disorders. It has also been established that abnormalities lipoprotein metabolism an important role in atherogenesis non-menopausal females are protected from atherosclerotic events relative to menopausal males. This study aimed investigate the relationship such as...

schizophrenia is a mental disorder painful with prevalence of about 1% in the world.  nowadays, there is no experimental test aiding the accurate diagnosis of schizophrenic patients but recently quantitative determination of some serum proteins led to many investigations on the roles of these in neuropsychiatric.in the present study, our aim is to quantitative determination apoa1 and igm betwee...

background & aim:  this study aimed to determine the relationship between lipid and apolipoprotein b-100 (apo b-100) levels in maternal and umbilical cord sera as well as the effects of these components on anthropometric measurements of newborn infants. methods:this correlational study was performed on 85 appropriate for gestational age (aga) newborns and their mothers. for analysis, 5 ml of ma...

familial defective apolipoprotein (apo) b 100 (fdb) causes early-onset coronary heart diseases (chd). it is produced by r3500q mutation of the apob gene resulting in decreased binding of ldl to ldl receptor. we screened the apo b gene for r3500q mutation in 130 hypercholesterolemic patients, among whom 30 patients met criteria of familial hypercholesterolemia (fh). the prevalence of r3500q alle...

background: alzheimer's disease as a neurodegenerative disorder is the commonest type of dementia. a growing number of genes have been reported as the risk factors, which increase the susceptibility to alzheimer's disease. apolipoprotein e ( apoe) , which its ε4 allele has been reported as a risk factor in late onset alzheimer's disease (ad), is the main cholesterol carrier in the brain. the ma...

  Abstract   Background: Recently, small dense low density lipoprotein (sdLDL) has been   highlighted as a new risk factor for the coronary artery disease (CAD).Small dense   LDLs are believed to be atherogenic since these particles are taken up more easily by   arterial wall. They are readily oxidized and have reduced affinity for low density   lipoprotein (LDL) receptor and increased affinity...

background: familial chylomicronemia syndrome is a rare disorder of lipoprotein metabolism due to familial lipoprotein lipase or apolipoprotein c-ii deficiency or the presence of inhibitors to lipoprotein lipase. it manifests as eruptive xanthomas, acute pancreatitis, and lipaemic plasma due to marked elevation of triglyceride and chylomicrons levels. case presentation: we report a rare case of...

background: follicular fluid (ff) plays an important role in oocytes and embryo development, which may contribute to ivf/icsi success rate. objective: the aim of this study was to investigate the correlation between cholesteryl ester transfer protein (cetp) level in ff and the success rate of ivf/icsi. materials and methods: in a cross-sectional study, ff samples, ff samples were obtained from ...