background it has been elucidated that berberis vulgaris (barberry) can alleviate morphine withdrawal syndrome. also it has been reported that aqueous extract of barberry possibly have inhibitory effect on nmda receptors. objectives in this study, we decided to evaluate the effects of aqueous extract of b. vulgaris fruit on morphine tendency in mice using conditioned place preference (cpp) meth...

PURPOSE To determine the kinetics of tumor necrosis factor (TNF) and interleukin-6 (IL-6) in serum and aqueous humor of rats with different susceptibilities to endotoxin-induced uveitis (EIU), after footpad injection of lipopolysaccharide (LPS). METHODS Samples were collected from EIU-susceptible Lewis rats and EIU-resistant Brown Norway (BN) rats for up to 72 hours after LPS injection. Speci...

objective(s) portulaca oleracea l. is a herbaceous weed from portulacaceae family. it can be found in many parts of the world. modern pharmacological studies have demonstrated that p. oleracea have antioxidant effects. the protective effect of aqueous and ethanolic extract of p. oleracea against cisplatin-induced renal toxicity was studied in rats. materials and methods single intraperitoneal i...

background: inflammation is a dynamic process that is elicited in response to various harmful stimulantsthat may threaten the well-being of the host. herbs have been traditionally used as anti-inflammatory agents since very early times. rubia tinctorum l. is one of these herbs that havebeen used for treating inflammatory diseases in iranian traditional medicine. objective: this study aims at co...

objective: the beneficial effects of clove on toothache have been well documented. we have also previously shown the analgesic effects of clove essential oil. the present work was done to investigate the analgesic effects of the aqueous extract of clove using hot plate test. the possible role of opioid receptors in the analgesic effects of clove was also investigated using naloxone. materials a...

PURPOSE To determine in rabbits whether periocular injection of ketorolac tromethamine effectively delivers the drug to the eye and, if so, whether this is efficacious in the treatment of experimental uveitis. METHODS Ketorolac was administered by anterior subconjunctival injection, posterior periocular injection, intramuscular injection, or topical eye drops. The aqueous and vitreous were as...

UNLABELLED Purpose To investigate the elimination rate of voriconazole after intravitreal injection in rabbits. METHODS Intravitreal injections of 35 microg/0.1 mL voriconazole were administered to rabbits. Vitreous and aqueous humor levels of voriconazole were determined at selected time intervals (1, 2, 4, 8, 16, 24, and 48 hours), and the in vitreous half-life was calculated. Four to six e...

Aqueous fluorophotometric, tracer localization and modeling methods were combined to document the existence of a pathway in the normal rabbit for the diffusion of proteins from the ciliary and iridial process stromas through the iris stroma into the aqueous humor of the anterior chamber. A new custom-conjugated tracer, fluoresceinated horseradish peroxidase (F-HRP), was used. Anesthetized rabbi...

the effect of aqueous extract of nepata glomerulosa boiss. aerial parts on morphine withdrawal syndrome was investigated in mice. dependence was induced by subcutaneous injections of morphine for 3 consecutive days. on day 4, morphine was injected 2 h prior to intraperitoneal injection of naloxone. the number of jumps during a 20 min. period after naloxone injection was considered as a measure ...