The sensitivity of two Gram positive (Staphylococcus aureus and Bacillus subtilis) and two Gram negative (Escherichia coli and Pseudomonas aeruginosa) pathogenic multi-drug resistant bacteria was tested against the crude extracts (cold aqueous, hot aqueous, and methanol extracts) of leaves and seeds of Argemone mexicana L. (Papaveraceae) by agar well diffusion method. Though all the extracts we...

Alcohol and aqueous extracts from the leaves of Argemone mexicana were investigated for their anthelmintic activity against Pheretima posthuma and Ascardia galli. Five concentrations (6.25, 12.5, 25, 50 and 100 mg/ml) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worms. Both the extracts exhibited significant anthelmint...

Fractionation of the chloroform extract from the aerial part of Argemone mexicana led to the isolation of two benzophenanthridine-type alkaloids, N-demethyloxysanguinarine and pancorine; three benzylisoquinoline-type alkaloids, (+)-1,2,3,4-tetrahydro-1-(2-hydroxymethyl-3,4-dimethoxyphenylmethyl)-6,7-methylenedioxyisoquinoline, (+)-higenamine and (+)-reticuline. Among them, N-demethyloxysanguina...

In vivo and in vitro sublethal exposure of abrin, glycyrrhizin (active component of Abrus precatorius seed and root), sanguinarine, protopine (Argemone mexicana seed) and oleandrin (Nerium indicum leaf) inhibited the acetylcholinesterase, lactic dehydrogenase, acid and alkaline phosphatase activity in the nervous tissue of Lymnaea acuminata. The succinic dehydrogenase activity in the nervous ti...

Background: Medicinal plants are widely used to treat infectious diseases, metabolic disorders and cancer. Argemone mexicana L. (A. mexicana), commonly found on desolate land of Marathwada (Maharashtra, India) has been used to treat oral cavity infections. Methods: In this study, cold aqueous and methanolic extracts were prepared from A. mexicana stem and leaves. These extracts were tested for ...

The Papaveraceae, informally known as the poppy family, are an ethnopharmacologically important family of 44 genera and approximately 760 species of flowering plants. The present work offers a review addressing the detailed chemistry and pharmacology of Argemone mexicana L. regarded as one of the most significant plant species in traditional system of medicine. The plant is used in different pa...