This work demonstrates that, in accord with metal catalysis, ferrocene could be an excellent scaffold for organocatalysts. The simple and easily accessible bifunctional ferrocene-based squaramide-phosphine shows high enantioselectivity in the intramolecular Morita-Baylis-Hillman reaction of 7-aryl-7-oxo-5-heptenals, giving a variety of 2-aroyl-2-cyclohexenols in up to 96% ee.

The ruthenium(II)-catalyzed ortho-C–H arylation of 2-aroyl-imidazoles with aryl bromides and chloride is reported. An imidazole ring functions both as a masked ester directing group for C–H activation. A variety functional groups are tolerated under the reaction conditions. arylated final products could be easily converted into corresponding esters amide.

4-aroyl-5-aryl-2,3-furandiones and N,N-dialkyl urea combine with loss of water yielding the pyrrole2,3-dione derivatives in moderate yields (47-68%). Then, these compounds were converted into 2(1H)quinoxalinones with various 1,2-phenylenediamines. The structures and characterizations of the synthesized compounds were established by the Hand C-NMR, IR and elemental analysis.

The regioselective three-component condensation of azomethine ylides derived from isatins and α-amino acids with acrylamides or aroylacrylic acids as dipolarophiles has been realized through a one-pot 1,3-dipolar cycloaddition protocol. Decarboxylation of 2'-aroyl-2-oxo-1,1',2,2',5',6',7',7a'-octahydrospiro[indole-3,3'-pyrrolizine]-1'-carboxylic acids is accompanied by cyclative rearrangement w...

The first example of an asymmetric organocatalyzed decarboxylative aldol reaction of β-ketoacids (aroylacetic acids) with α-ketophosphonates that produces a quaternary chiral centre has been developed. A quinidine based bifunctional urea derivative was identified as the preferred catalyst affording γ-aroyl tertiary α-hydroxyphosphonates in good yield and enantioselectivity. The 31P NMR spectros...

A whole family of annelated 4H-thiopyran-4-ones as the core structural unit was readily synthesized in good yields by a microwave-assisted coupling-addition-S(N)Ar (CASNAR) sequence starting from readily available (het)aroyl chlorides, alkynes and sodium sulfide nonahydrate in a consecutive one-pot three-component reaction. All representatives display a pronounced halochromicity of the absorpti...

The asymmetric unit of the title compound, C(26)H(20)O(4), contains two independent conformers. The aromatic rings of the aroyl groups are twisted with respect to the naphthalene ring systems to form dihedral angles of 66.58 (6) and 66.45 (6)° in one conformer, and 75.00 (7) and 81.17 (6)° in the other conformer. The crystal packing is stabilized by weak inter-molecular C-H⋯O hydrogen bonds and...