A 3-D beam scanning antenna array design is proposed that gives a whole 3-D spherical coverage and also suitable for various radar and body-worn devices in the Body Area Networks applications. The Array Factor (AF) of the proposed antenna is derived and its various parameters like directivity, Half Power Beam Width (HPBW) and Side Lobe Level (SLL) are calculated by varying the size of the propo...

BACKGROUND Intergenic variations on chromosome 4q25, close to the PITX2 transcription factor gene, are associated with atrial fibrillation (AF). We therefore tested whether adult hearts express PITX2 and whether variation in expression affects cardiac function. METHODS AND RESULTS mRNA for PITX2 isoform c was expressed in left atria of human and mouse, with levels in right atrium and left and...

The heterogeneous presentation and progression of atrial fibrillation (AF) implicate the existence of different pathophysiological processes. Individualized diagnosis and therapy of the arrhythmogenic substrate underlying AF may be required to improve treatment outcomes. Therefore, this single-center study aims to identify the arrhythmogenic areas underlying AF by intra-operative, high-resoluti...

BACKGROUND The long-term probability of developing atrial fibrillation (AF) considering genetic predisposition and clinical risk factor burden is unknown. METHODS We estimated the lifetime risk of AF in individuals from the community-based Framingham Heart Study. Polygenic risk for AF was derived using a score of ≈1000 AF-associated single-nucleotide polymorphisms. Clinical risk factor burden...

The aim of this study was to develop an improved technique for DNA extraction from 1 ml of uncultured AF from patients with a gestational age less than 16 weeks and to allow the use of array-CGH without DNA amplification. The DNA extraction protocol was tested in a series of 90 samples including 41 of uncultured AF at less than 16 weeks of gestation. Statistical analyses were performed using li...

background: new-onset atrial fibrillation (af) after cardiac surgery contributes to increased morbidity, hospital length of stay, and resource utilization. although many aspects of af after cardiac surgery have already been elucidated, the mechanism by which cardiac surgery predisposes patients to af has hitherto remained unknown. recent evidence supports the notion that blood transfusion enhan...

BACKGROUND Atrial fibrillation (AF) is the most common arrhythmia in women and is associated with higher rates of stroke and death. Rates of AF are lower in African American subjects compared with European Americans, suggesting European ancestry could contribute to AF risk. METHODS The Women's Health Initiative (WHI) Observational Study (OS) followed up 93,676 women since the mid 1990s for va...

We provide a formal mathematical definition of the Shortest Paths for All Flows (SP-AF) problem and provide many efficient algorithms. The SP-AF problem combines the well known Shortest Paths (SP) and Bottleneck Paths (BP) problems, and can be solved by utilising matrix multiplication. Thus in our research of the SP-AF problem, we also make a series of contributions to the underlying topics of ...

Atrial fibrillation (AF) is a progressive disorder that increases with age. Obesity is an important risk factor for AF. Pericardial fat is an active adipose tissue in close proximity to the heart and has been shown to be a risk factor for structural as well as coronary artery disease independent of body mass index. Recent studies suggest a role of epicardial fat in atrial remodeling as well as ...