Stiffness of large arteries has been long recognized as a significant determinant of pulse pressure. However, it is only in recent decades, with the accumulation of longitudinal data from large and varied epidemiological studies of morbidity and mortality associated with cardiovascular disease, that it has emerged as an independent predictor of cardiovascular risk. This has generated substantia...

BACKGROUND Adipocyte fatty acid binding protein (A-FABP) is a novel fat-derived circulating protein, which is independently and positively associated with atherosclerosis. The present study evaluated the relationship between fasting serum A-FABP and central arterial stiffness in geriatric adults. METHODS Fasting blood samples were obtained from 87 geriatric patients and the serum A-FABP level...

Background: Arterial stiffness is one of the predictors of cardiovascular event. Arterial stiffness is commonly measured by pulse wave velocity between the carotid and femoral arteries. Recently the arterial stiffness index which is measured by computerized oscillometry at the upper arm was developed. As this procedure is a convenient means of measuring pulse wave velocity, we considered it sui...

Introduction: Arterial stiffness is an important predictor of cardiovascular risk. Several indices have been  introduced to estimate the arterial stiffness based on the changes in the brachial blood pressure. Since the  substitution  of  the  blood  pressure  changes  in  the  central  arteries  such  as  carotid  with  the  blood  pressure  changes in the brachial results in error in the blood...

OBJECTIVES We hypothesized that one minus the slope of diastolic on systolic blood pressure in individual 24-h ambulatory blood pressure recordings (ambulatory arterial stiffness index) might reflect arterial stiffness and predict cardiovascular mortality. METHODS In volunteers and a population recruited in China, we studied concordance between ambulatory arterial stiffness index and establis...

BACKGROUND Hypertension is strongly associated with cardiovascular disease. It has been reported that arterial stiffness is related to cardiovascular mortality and morbidity in hypertensive patients and that the physiological evaluation of arterial stiffness may assist clinicians in the early detection of atherosclerosis. SUMMARY It has been demonstrated that increased arterial stiffness is a...

The process of population ageing that is occurring in developed societies represents a major challenge for the health system. Cardiovascular diseases (CVD) are the most common cause of morbidity and mortality in the world, representing half of the deaths in people over 65 years old. Among the CVD, systemic arterial hypertension is related to more than half of those outcomes [1]. The non-modifia...

A significant association between increased arterial stiffness and the development of cardiovascular disease has led to the increased use of arterial stiffness in the clinical assessment of cardiovascular risk. Various methods are currently available. With advances in technology, the assessment methods have become easy to use and more acceptable to patients. However, the different techniques th...