Background:Chronic synovitis is one of the most important complications in haemophilic patients. Rifampin is anantibiotic which its intra-articular injecion leads to destruction of the synovial membrane of haemophilic patientsmedically.Materials and Methods: Between September 2003 and November 2005, we administered intra-articular rifampinin ١۶ haemophilic joints of ٨ haemophilic patients.Resul...

Background: Recent studies have provided evidence that integrins play roles in recognition of mechanical stimuli and its translation into a cellular response. Integrin signaling may be regulated by a number of mechanisms including accessory proteins such as CD98 (4F2 antigen). Objectives: To determine CD98 expression by human articular chondrocytes and its involvement in human articular mechano...

knee surgery. the purpose of this study was to assess the analgesic effects of intra-articular injection of a dexmedetomidine following knee arthroscopy. methods:   forty six patients schadualed for arthroscopic knee surgery under general anaesthesia, were randomly devided into two groups. intervention group received 1μg/kg dexmedetomidine (d) and isotonic saline. control group received 25ml is...

conclusions although postoperative intra-articular meperidine is a better alternative for bupivacaine, their combination could improve their analgesic effects compared with each other alone. results the bupivacaine-meperidine group had better duration of postoperative analgesia (p = 0.001), latter first analgesic request (p ≤ 0.001), lower total fentanyl consumption in first 24 hours after the ...

conclusions the odscp has many advantages over the other type of plates. it can help the surgeon to operate with a relaxed mind and it is advisable for high tibial medial open wedge osteotomies. results the mean follow-up time was 9.33 ± 1.87 month. the average age was 45.13 ± 7.25 years. three patients were male and 13 patients were female. the lysholm score showed a significant difference bef...

abstract   background: the tibial diaphyseal fractures are the most common type of long bone fractures encountered by most orthopedic surgeons. in accordance with descriptive indices of tibia fractures on the basis of their location in the bone, distal tibia fractures have the second incidence of all tibia fractures after the middle tibia fractures. the purpose of the study was to assess the co...

two rare cases of extra-articular diffuse variant giant cell tumor of the tendon sheath are presented, at the elbow of a 68-year-old female and the foot of a 56-year-old male. both patients presented with a palpable masses and marginal excision was performed; histological sections confirmed the diagnosis of extra-articular giant cell tumor. no adjuvant therapy was administered. at the last foll...

background: previous studies have shown that galectin-3, a member of lectin family, is expressed in developing cartilage in mouse embryo and also in growth plate of long bones.   objective: in the present work, the expression pattern of galectin-3 in normal and various grades of osteoarthritic (oa) human articular cartilage has been studied.   methods: using immunohistochemistry and standard we...

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background: while articular chondrocytes are among those appropriate candidates for cartilage regeneration, the cell dedifferentiation during monolayer culture has limited their application. several investigations have indicated the usefulness of alginate, but the topic of proliferation and differentiation of chondrocytes in alginate culture has still remained controversial. methods: rat articu...