Artificial sweeteners are food additives whose use has been controlled by European Parliament guidelines. The method described in this application note, shows how LC-MS/MS can be used to simultaneously detect and confirm the presence of several artificial sweeteners. The method is both quicker than conventional non LC-MS/MS methods and more sensitive. This has meant that these compounds can be ...

America's obesity epidemic has gathered much media attention recently. A rise in the percent of the population who are obese coincides with an increase in the widespread use of non-caloric artificial sweeteners, such as aspartame (e.g., Diet Coke) and sucralose (e.g., Pepsi One), in food products (Figure 1). Both forward and reverse causalities have been proposed. While people often choose "die...

It has been widely documented that municipal wastewater treatment plant effluents are a major source of artificial sweeteners to surface waters. However, in rural areas, the extent to which septic systems contribute these same compounds to groundwater aquifers is largely unknown. We examined the occurrence of four commonly used artificial sweeteners in an unconfined sand aquifer that serves as ...

High-potency or artificial sweeteners have historically been considered inert compounds without physiological consequences other than taste sensations. However, recent data suggest that some of these sweeteners have biological effects that may impact human health. Furthermore, there are significant gaps in our current knowledge of the pharmacokinetics of these sweeteners, their potential for "s...

diabetes and obesity are two common human disorders that affecting human health and invite various diseases and disorders in normal body functions. these diseases are very common worldwide. diabetes occurs when high blood sugar levels develop. this happens when body can’t make and use all of the insulin it needs to blood sugar normally to keep blood sugar levels as normal as possible to control...