CONTEXT Cholinesterase (ChE) specific activity is the ratio of ChE activity to ChE mass and, as a biomarker of exposure to cholinesterase inhibitors, has a potential advantage over simple ChE activity. OBJECTIVE To examine the association of several potential correlates (serum arylesterase/paraoxonase activity, serum albumin, sex, age, month of blood collection, and smoking) with plasma ChE s...

OBJECTIVE Paraoxonase is a high density lipoprotein-associated anti-oxidant enzyme. The aim of this study was to investigate the serum paraoxonase and arylesterase activities and associations between these enzymes and lipid hydroperoxide (LOOH) in preeclamptic patients. MATERIALS AND METHODS The study included 47 preeclamptic (25 severe and 22 mild preeclampsia cases) and 20 normotensive heal...

Background/aim: The main aim of this study was to investigate serum total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and arylesterase levels in pregnant women with placenta accreta and to compare those with age-matched healthy pregnant women. Materials and methods: A total of 27 pregnant women who had clinically and pathologically proven placenta accreta...

objective: the aim of this study was to investigate the effect of pomegranate juice (pj) on the paraoxonase and arylesterase activity of human serum paraoxonase( pon1). material and method: fifty patients with type 2 diabetes mellitus consumed 200 ml of pj daily for a period of 6 weeks. blood was collected from the patients before and after pj consumption after 12 h of fasting. blood sugar, tot...

OBJECTIVE Diminished serum paraoxonase and arylesterase activities (measures of paraoxonase-1 [PON-1] function) in humans have been linked to heightened systemic oxidative stress and atherosclerosis risk. The clinical prognostic use of measuring distinct PON-1 activities has not been established, and the genetic determinants of PON-1 activities are not known. METHODS AND RESULTS We establishe...

Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics. PON1 activity varies widely among individuals and ethnic groups, partly related to polymorphisms. The aim of this study was to determine the activities of PON1 and arylesterase including the phenotype distribution of PON1 in asthmatic pat...

OBJECTIVE Newborn infants, particularly preterm infants, are at greater risk of oxidative stress because of an imbalance between high oxidant loads and immature antioxidant defenses. In several studies, the activities of serum paraoxonase (PON) and arylesterase (ARE) have been found to decline in patients under increased oxidative stress. We investigated the relationships between PON-1 and ARE ...

A novel thermostable arylesterase, a 35-kDa monomeric enzyme, was purified from the thermoacidophilic archaeon Sulfolobus solfataricus P1. The optimum temperature and pH were 94 degrees C and 7.0, respectively. The enzyme displayed remarkable thermostability: it retained 52% of its activity after 50 h of incubation at 90 degrees C. In addition, the purified enzyme showed high stability against ...

The research involved study the relation between FGF23 and some of biochemical parameters related to chronic kidney disease (Glutathion GSH arylesterase ARE enzymes,ceruloplasmin ,Malondialehyde ,glucose ,cholesterol ,triglyceride ,LDL ,VLDL,HDL)in serum blood patients compared with control group,the result demonstration is a significant increase in mean concentration rate was (324.06± 291.1 pg...

BACKGROUND Paraoxonase 1 (PON1) activity and von Willebrand factor (VWF) release are associated with lesion initiation in atherosclerosis. Diabetes can complicate coronary artery disease (CAD) due to the production of advanced glycation end products. This study evaluated PON1 activity and VWF levels in non-post-acute coronary syndrome, stable CAD (SCAD) patients without diabetes. MATERIAL/MET...