fertilization involves direct interaction of the sperm and oocyte, fusion of the cell membranes and :union: of male and female gamete genomes. the completion of this process and subsequent embryo development depend in part on the inherent integrity of the sperm dna. sperm genome quality has been emphasized for several years as playing a major role in early embryogenesis. there is clinical evide...

background:   objective: comparison of albumin and cabergoline in the prevention of ohss.   materials and methods: 95 high risk infertile women for ohss (more than 20 follicles in both ovaries at day of human chorionic gonadotropin (hcg) injection) were randomly divided into two groups. first group including 48 women received 10 unit intravenous albumin at starting oocyte retrieval, and second ...

background: despite numerous developments in the field of assisted reproduction the implantation rate remains low .recent studies suggested that local injury to endometrium in controlled ovarian hyper stimulation cycle improves implantation rate. studies have attempted to intervene in the development of endometrium. objective: the aim of the present study was the exploration of the possibility ...

background: public interest in assisted reproductive technology (art) has remained high since the birth of the world’s first in vitro fertilization baby, louise brown, in the united kingdom. art allows scientists to manipulate the fertilization process in order to bypass some pathological obstacles such as blocked fallopian tubes and non-functioning ovaries in the females, and blocked vas defer...

background: detection of best predictor of ovarian reserve in patients with temporarily or consistently elevated early follicular phase serum levels of fsh is one of the most important goals in assisted reproductive technique (art). objective: to evaluate whether high level of anti-mullerian hormone level is related to success of art in patients with temporarily or consistently elevated early f...

objective: there is a large amount of information published about art infants worldwide but apparently the similar data did not published by iranian art centers till now. this study is a comparative study for developmental assessment of these infants. materials and methods: in one case- control study 400 art ' infants have been compared with 420 nc ' infants. their developments have been assess...

background: implantation failure of blastocyst is one of the main reasons of failure to become pregnancy following use of assisted reproductive techniques. hla-g, one of the non-classic hla subtypes, seems to have a vital role in neutralizing of mother immune system. according to importance of ins/del polymorphism of hla-g in regulation of hla-g expression, it seems that this polymorphism has a...

apparent rise in the incidence of infertility in females and the trend shifting towards delayed child bearing brought up the concept of ovarian ageing. women in their early thirties show poor ovarian reserve which is an entity named as early ovarian ageing. early ovarian ageing is mostly genetically determined, but acquired modifiable factors like smoking, or ovarian surgery have some roles. in...

there has been a dramatic rise in the use of assisted reproductive technologies (art), including in vitro fertilization (ivf) throughout the world over the past three decades. because they represent >1% of the birth cohorts in many developed countries, much attention is being paid to the health and well-being of art children. children born after assisted reproductive techniques (art) have an in...

Background: Infertility leads to profound human suffering, particularly on the women. Women's lack of pregnancy is both physically and socially visible, especially in high fertility societies where women are typically blamed for reproductive failures, even in cases of male infertility. Childless women are more likely to be the victims of domestic violence and may also endure various forms ...