BACKGROUND Classically, the ST-T configuration in the electrocardiogram of patients with left ventricular hypertrophy is said to have a typical pattern of ST depression together with asymmetrical T wave inversion (the so-called left ventricular strain pattern). However, many patients with left ventricular hypertrophy may also have ischaemic heart disease. To revise the electrocardiographic crit...

BACKGROUND Analyzing the determinants of systolic anterior motion of the mitral valve and consequent left ventricular outflow tract (LVOT) obstruction in patients with asymmetrical septal hypertrophy requires a comprehensive 3-dimensional analysis of mitral leaflet (ML) area, papillary muscle (PM) geometry, and the distribution of left ventricular hypertrophy. METHODS AND RESULTS Real-time 3-...

Background—Analyzing the determinants of systolic anterior motion of the mitral valve and consequent left ventricular outflow tract (LVOT) obstruction in patients with asymmetrical septal hypertrophy requires a comprehensive 3-dimensional analysis of mitral leaflet (ML) area, papillary muscle (PM) geometry, and the distribution of left ventricular hypertrophy. Methods and Results—Real-time 3-di...

In 1957, Brock1 made the distinction between congenital subaortic stenosis characterized by a fibrous ridge and “functional subvalvar stenosis” resulting from “muscular hypertrophy,” describing 3 patients with the latter. Brock initially attributed the hypertrophy and resultant outflow obstruction to systemic hypertension, a conclusion he withdrew in a 1959 publication.2 Between these 2 publica...

In a recent paper, one of us (Teare, 1958) described 8 examples of a hitherto little recognized type of heart disease under the title Asymmetrical hypertrophy of the heart in young adults. The lesion was thought to be a benign tumour or hamartoma and was confined to the left ventricle, especially in the region of the septum. One of these patients, a woman of 21, had been under the care of Hamme...

FOLLOWING Brock's' recognition that hypertrophied muscle in the left ventricular outflow tract could obstruct left ventricular outflow, much interest has centered on the nature of this hypertrophy. Initial reports suggested that concentric hypertrophy of the left ventricle was the underlying cause of the obstruction of the outflow tract. -3 Following Teare's4 description of asymmetrical hypertr...

A 64-year-old man presented with several weeks of intermittent irregular palpitations. He had no prior history of cardiac disease, hypertension or syncope. A 12-lead ECG revealed sinus rhythm with premature atrial and ventricular contractions and high QRS voltages consistent with LV-hypertrophy. Cardiac MR revealed asymmetrical septal hypertrophy and marked mid-myocardial hyperenhancement of th...

Unexpected findings on bone scintigraphy such as asymmetrical uptake in extremities may cause confusion for the diagnosis. The authors describe three cases of accidental intraarterial injection of Tc-(99m) methylene diphosphonate ((99m)Tc-MDP) on the antecubital region and discuss the findings and differential diagnosis.