Case Description- A pigeon with an abnormal mass on right wing was referred to the Veterinary Clinic of Shahid Bahonar University of Kerman. Treatment and Outcome- The mass was removed surgically and histopathologic examination was done. Microscopic findings revealed a stori-form pattern of atypical and pleomorphic spindle-shape tumor cells with histiocytes and too many thick wall capillari...

OBJECTIVES To identify pretest characteristics of cerebrospinal fluid (CSF) specimens that will allow the rational use of flow cytometric analysis (FCA) in the diagnosis of hematologic malignancy. METHODS Retrospective data were collected on 501 consecutive CSF samples submitted for FCA. RESULTS A positive diagnosis of hematologic malignancy was made in 41 specimens (8.2%). Blasts or atypic...

Sézary cells (SC) (synonyms: mycosis cell, Lutzner cell, cerebriform lymphocytes, Atypia Cellules Monstreuses or monster cell) are atypical lymphocytes with a grooved or cerebriform nucleus seen both in tissue and blood. They are characteristically seen in cutaneous T cell lymphomas including mycosis fungoides (MF). The Sézary cell is named after the French dermatologist Sézary A (1880-1956). S...

Lui, W. Y., and Chang, W. K. (1972). Archives of Disease in Childhood, 47, 643. Cytomegalovirus mononucleosis in Chinese infants. Two Chinese infants had cytomegalovirus inclusion disease presenting as persistent pneumonia and thrombocytopenic purpura, respectively. Both had lymphadenopathy, hepatosplenomegaly, pneumonia, and more than 14% atypical lymphocytes in the peripheral blood at some st...

A previously healthy 26-year-old woman underwent a routine Papanicolaou test a few weeks after first coitus. As the results suggested atypical squamous cells of uncertain significance, she was referred to a gynecologist. The uterine cervix appeared grossly normal. Microscopic examination of the blind biopsies of the cervix demonstrated diffuse infiltration of atypical large lymphoid cells admix...

t/nk cell proliferative ebv associated disease is a rare one which is more common in eastern asian countries. ebv is originally associated with b cells, and ebv associated t cell lymphoma is so rare. hence we decided to describe a patient treated with misleading diagnoses such as tb and sarcoidosis for almost two years. the liver was biopsied after admission in this center, and gastric and colo...

Hydroa vacciniforme (HV) is a photosensitivity disorder in childhood characterized by recurrent vacciniform vesicles, necrotic ulcers, and scars on sun-exposed areas. HV-like lymphoma is a rare variant of cutaneous T-cell lymphoma. HV, atypical HV and HV-like lymphoma belong to the spectrum of Epstein-Barr virus (EBV)-associated lymphoproliferative disorders. We report a fatal case of HV-like l...

During an immune response against a microbial pathogen, activated naive T lymphocytes give rise to effector cells that provide acute host defense and memory cells that provide long-lived immunity. It has been shown that T lymphocytes can undergo asymmetric division, enabling the daughter cells to inherit unequal amounts of fate-determining proteins and thereby acquire distinct fates from their ...

T his peripheral blood (PB) smear from a 24-year-old man with retroperitoneal lymphadenopathy and a white blood cell count of 77 3 10 cells/L (66% lymphocytes) showed variably-sized atypical lymphocytes with irregular nuclear contours and basophilic vacuolated cytoplasm including numerous flower cells and apoptotic cells (panel A). Hallmark cells with reniform nuclei, small to large in size, we...