STUDY DESIGN A case controlled study with prospective data collection. PURPOSE To evaluate the early influence and the final consequence of demineralized bone matrix (DBM) on auto-local bone as a graft enhancer in posterior lumbar interbody fusion (PLIF). OVERVIEW OF LITERATURE DBM is known as an osteoinductive material; however, it has not been clearly recognized to enhance auto-local bone...

Abstract Glioblastoma (GBM) is a common, malignant brain tumor. While it rarely metastasizes to distant organs, the diffuse invasion of glioma cells within makes difficult resect. P21 (Waf-1) cyclin-dependent kinase inhibitor that plays an essential role in cell growth arrest, terminal differentiation, and apoptosis. Thus, existence natural variants p21 could be linked specific cancer. The purp...

Abstract Background and Aims Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited, complex disease, cystogenesis phenotypic changes in this disorder being not yet fully understood. Recently, arginine, important for renal cells metabolism, was proved to play role ADPKD physiopathology (1). The inability of recycle or synthesize intracellular arginine through the urea cycle define...

The Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3 are major hemoglobinases and potential antimalarial drug targets. Our previous studies demonstrated that these enzymes are equipped with specific domains for specific functions. Structural and functional analysis of falcipains showed that they have unique domains including a refolding domain and a hemoglobin binding domain...

nanocrystalline particles of barium hexaferrite has been prepared by the sol–gel auto- combustion method using iron and barium nitrate with a ba:fe molar ratio of 1:10. the effect of fuel such as citric acid and aspartic acid was investigated on the structure and magnetic properties of nanoparticles. the results revealed that the formation of barium hexaferritefine particles is influenced by mo...

zro2 nanopowder was prepared by the sol-gel auto-combustion method. the product was characterized by x-ray diffraction (xrd), energy dispersive analysis of x-ray (edx) and scanning electron microscopy (sem). the average crystalline size of zro2 was obtained 62 nm. also, photocatalytic removal of nitrophenol from aqueous solution by using nanoscale zro2 under uv light irradiation was studied. th...

Proenzymes with various lengths of propeptides have been observed in GluV8 from Staphylococcus aureus and GluSE from S. epidermidis. However, the production mechanism of these proenzymes and roles of truncated propeptides have yet to be elucidated. Here we demonstrate that shortening of propeptide commonly occurs in an auto-catalytic manner in GluV8-family members, including those from coagulas...