autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. hepatitis c virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis c virus infection and some autoimmune disease has been st...

autoimmune hepatitis is a chronic hepatitis that occurs in children and adults of all ages. diagnosis is based upon characteristic serologic and histologic findings and the exclusion of other forms of chronic liver disease. guidelines issued by the aasld suggest the following diagnostic considerations: the diagnosis should be made in patients with compatible clinical signs, symptoms, and labora...

introduction coexistence of wilson’s disease and autoimmune hepatitis has been rarely reported in english literature. in this group of patients, there exist features of both diseases and laboratory and histopathological studies may be misleading. medical treatment for any of these entities, per se, may result in poor response. therefore, by considering the acute hepatitis resembling wilson’s di...

introduction and aims: impact of treatment on progression of fibrosis in autoimmune hepatitis (aih) is unknown. we assessed the changes in liver fibrosis before and after treatment among these patients. materials and methods: nineteen aih patients who had paired liver biopsies were studied. of these, seven had been treated with 6 months of cyclosporine-a and the rest with 6 months of prednisolo...

α-Interferon is an antiviral agent used in treatment of chronic hepatitis B. Triggering of the underlying autoimmune disease or exacerbation of pre-existing auto immune disease is documented with α-interferon, but there are few reports about occurrence of autoimmune disorders such as systemic lupus erythematosus, Vitiligo, hypo and hyperthyroidism after administration of α-interferon in the lit...

OBJECTIVE Celiac disease is an autoimmune disorder in which the risk of autoimmune liver disease is high. Autoimmune hepatitis is a chronic and progressive entity and the risk of its being associated with other autoimmune disorders such as celiac disease is high also. The aim of this study was to determine the prevalence of celiac disease in patients with autoimmune hepatitis and vice versa. ...

Hepatitis A infection is usually a self–limited disease during childhood. Autoimmune manifestations are rarely reported among patients with HA infection. We describe a previously healthy 6-yr-old male with acute hepatitis A who developed immune thrombocytopenia.

BACKGROUND Drugs and herbal products can induce autoimmune hepatitis. We assessed frequency and clinical outcomes of patients suffering from drug-induced autoimmune hepatitis. METHODS All patients with drug-induced liver injury admitted between 2000 and 2011 were retrospectively studied. Diagnoses of drug-induced autoimmune hepatitis and idiopathic autoimmune hepatitis were made according to ...