A system for the numbering of mutants of avian sarcoma and leukosis viruses is proposed.

The RNAs of several classes of avian and murine RNA tumor viruses were compared. The 60-70s RNA complex of cloned nondefective avian sarcomaviruses contains only 30-40s RNA species of class a, which are larger than the 30-40s RNA species of class b found in avian transformation-defective or leukosis viruses. The RNA of a recombinant avian sarcoma virus, carrying a host range marker of a leukosi...

We report the complete genome sequence of avian leukosis virus subgroup J (ALV-J) isolate PDRC-59831, which causes myeloid leukosis and hemangiomas in chickens. This is an American ALV-J isolate, which was found in a 38-week-old broiler breeder chicken on a farm in Georgia in 2007.

Basic fibroblast growth factor (bFGF) is overexpressed in most high-grade human gliomas, implying that it is involved in the pathogenesis of these tumors. To assess the biological effect of inappropriate production of bFGF in normal astrocytes, we developed a system for glia-specific gene transfer in transgenic mice. A transgene encoding the receptor for subgroup A avian leukosis virus and cont...

Thirteen oncogenic and necrotizing animal viruses were assayed in LIFE Sciences, Inc. (LSI)-specific pathogen-free Japanese quail and LSI-specific pathogen-free chicken embryo cell cultures. Nine viruses produced similar titers in the quail and chicken cell systems, whereas four viruses showed significantly higher titers in chickens. Young Japanese quail and chickens were inoculated with five s...

The disease called fowl paralysis, together with several other allied conditions classed together as the avian leukosis complex,^ causes a tremendous loss to the poultry industry. The paralysis form of this disease complex was first recognized in the United States along the eastern coast about 1920. During the last 20 years the avian leukosis complex has spread rapidly until few flocks of chick...

abstract: subgroup j avian leukosis virus (alv-j) was isolated in the late 1980s from meat-type chickens in the united kingdom. alv-j with exception of some acute variants, cause myeloid leukosis in meat-type chickens with long incubation period.in this study while the status of avian leukosis virus subgroup j in six different strain of broiler grandparent flocks of iran evaluated, the evaluati...

After an initial acute infection with cell killing, chicken or duck embryo fibroblasts infected in culture with reticuloendotheliosis viruses set up a chronic infection with no cell killing or morphological transformation. Essentially all of the chronically infected cells produced virus. The virus production was not sensitive to cytosine arabinoside or mitomycin C as was virus production in an ...