background: bacillus calmette-guérin (bcg) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. however, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. the disseminated bacillus calmette–guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. ...

background: although the efficacy of bacillus calmette-guerin (bcg) vaccine in the prevention of tuberculosis has been noted consistently, the use of bcg vaccine is not without risk. in this study we aimed to evaluate immunologically, children with complication of bcg vaccination in north of iran.materials and methods: this case-control study began in 30 jan 2013 and was completed in 2 jul 2015...

phosphodiesterases  (pde)  hydrolyse intracellular camp  and  cgmp  to  inactive  5’ monophosphates. decreased level of camp is involved in the pathogenesis of asthma. we and others have shown that phosphodiesterases were upregulated in the lung of allergic rats, and bacilli calmette-guérin (bcg) induced the production of camp in vitro. however, it is unclear how bcg’s effect asthma and whether...

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2016;5(S1) tau.amegroups.com Cite this abstract as: Cui J, Chen S, Yang Y, Zhu Y, Chen F, Shi B. Combination of intravesical chemotherapy and Bacillus Calmette-Guerin versus Bacillus Calmette-Guerin monotherapy in intermediateand high-risk non-muscle invasive bladder cancer: a systematic review and meta-analysis. Tr...

Intravesical Bacillus Calmette-Guérin (BCG) is an established treatment for high-risk superficial bladder cancer [Morales A, Eidinger D, Bruce AW. Intracavitary Bacillus Calmette-Guérin in the treatment of superficial bladder tumors.1976. J Urol 2002; 167: 891-893, Lamm DL, van der Meijden APM, Morales A et al. Incidence and treatment of complications of Bacillus Calmette-Guérin intravesical th...

We have used humanized mice, in which human immune cells differentiate de novo from transplanted cord blood progenitor cells, to study the human immune responses to infection with Mycobacterium bovis bacillus Calmette-Guérin and Mycobacterium tuberculosis. Granulomas with a core containing giant cells, human CD68(+) macrophages, and high bacilli numbers surrounded by a layer of CD3(+) T cells a...

PURPOSE Carcinoma in situ represents high grade anaplasia of the bladder mucosa. Intravesical immunotherapy with bacillus Calmette-Guérin is the gold standard treatment for patients with carcinoma in situ. Patients with carcinoma in situ refractory to bacillus Calmette-Guérin are candidates for major surgery such as radical cystectomy. We identified the maximum tolerated dose and the recommende...

Despite the widespread use of bacillus Calmette-Guérin vaccination, Mycobacterium tuberculosis infection remains globally the leading cause of death from a single infectious disease. The complicated and often protracted dynamics of infection and disease make clinical trials to test new tuberculosis vaccines extremely complex. Preclinical selection of only the most promising candidates is theref...

INTRODUCTION Thigh swelling in an infant can be a symptom of a simple benign condition or a life-threatening condition. We observed a cluster of thigh swelling episodes in infants in which the cause was Bacillus Calmette-Guérin-related cold thigh abscess. We report this unusual case series to raise awareness about this diagnosis. CASE PRESENTATIONS We performed a retrospective review of five ...