نتایج جستجو برای: balbc

تعداد نتایج: 98  

2015
Wolfgang Hohenforst-Schmidt Paul Zarogoulidis Joshua Stopek Efstratios Kosmidis Thomas Vogl Bernd Linsmeier Kosmas Tsakiridis Sofia Lampaki George Lazaridis Andreas Mpakas Robert Browning Antonis Papaiwannou Antonis Drevelegas Sofia Baka Vasilis Karavasilis Ioannis Mpoukovinas J Francis Turner Konstantinos Zarogoulidis Johannes Brachmann

Novel therapies for lung cancer are being explored nowadays with local therapies being the tip of the arrow. Intratumoral chemotherapy administration and local microwave ablation have been investigated in several studies. It has been previously proposed that lipiodol has the ability to modify the microenvironment matrix. In our current study we investigated this theory in BALBC mice. In total 1...

2016
Helena Giannakaki-Zimmermann Despina Kokona Sebastian Wolf Andreas Ebneter Martin S. Zinkernagel

PURPOSE Optical coherence tomography angiography (OCT-A) allows noninvasive visualization of retinal vessels in vivo. OCT-A was used to characterize the vascular network of the mouse retina and was compared with fluorescein angiography (FA) and histology. METHODS In the present study, OCT-A based on a Heidelberg Engineering Spectralis system was used to investigate the vascular network in mic...

2015
Wolfgang Hohenforst-Schmidt Paul Zarogoulidis Joshua Stopek Thomas Vogl Frank Hübner J Francis Turner Robert Browning Konstantinos Zarogoulidis Antonis Drevelegas Konstantinos Drevelegas Kaid Darwiche Lutz Freitag Harald Rittger

Lung cancer remains the leading cause of death in cancer patients. Severe treatment side effects and late stage of disease at diagnosis continue to be an issue. We investigated whether local treatment using 2-diethylaminoethyl-dextran methyl methacrylate copolymer with p53 (DDMC-p53) with or without cisplatin and/or microwave ablation enhances disease control in BALBC mice. We used a Lewis lung...

2016
Hong Yu Kim Vikhe Patil Chul Han Brian Fabella Barbara Canlon Shinichi Someya Christopher R. Cederroth

Gap detection or gap pre-pulse inhibition of the acoustic startle (GPIAS) has been successfully used in rat and guinea pig models of tinnitus, yet this system has been proven to have low efficacy in CBA mice, with low basal GPIAS and subtle tinnitus-like effects. Here, we tested five mouse strains (CBA, BalbC, CD-1, C57BL/6 and 129sv) for pre-pulse inhibition (PPI) and gap detection with varyin...

2017
Diego Aguilera Gabriela Andrea Balogh

Background: Conventional treatments for breast cancer involve surgery followed by radiation and hormonal therapy and/or chemotherapy. Some of these treatments have toxic side effects. Because drugs used in chemotherapy affect both cancer and normal cells to varying degrees, researchers are currently developing targeted drugs that only attack cancer cells without affecting normal cells. One appr...

ژورنال: دامپزشکی 2017

در جوندگان چرخه تولید مثل با نام چرخه فحلی شناخته می‌شود. این چرخه برخلاف سایر پستانداران اهلی، در جوندگان بسیار کوتاه مدت است. طول کوتاه چرخه فحلی این حیوانات را به مدلی مناسب برای مطالعات دستگاه تولید مثل، ارزیابی تاثیر عوامل بیرونی از جمله داروها، و تنش‌های تغذیه‌ای تبدیل نموده است. باتوجه به اهمیت شناخت دقیق ویژگی‌های چرخه تولید مثل در موش‌ها به ویژه در سویه‌های همخون از جمله Balb/c که در ق...

2016
Angèle Bénard Claudia Sala Gerd Pluschke

Buruli Ulcer is a neglected tropical disease leading to extensive disabilities and morbidity in West Africa. In this paper we sought to characterize various strains of Mycobacterium ulcerans (M.ulcerans) with different origins and laboratory passage records while refining a mouse model for Buruli ulcer. We described, compared and followed the kinetics of the histo-pathological outcome of infect...

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