Fragile X syndrome, a common form of inherited mental retardation, is caused by the loss of fragile X mental retardation protein (FMRP). We have previously demonstrated that dFmr1, the Drosophila ortholog of the fragile X mental retardation 1 gene, plays a role in the proper maintenance of germline stem cells in Drosophila ovary; however, the molecular mechanism behind this remains elusive. In ...

BACKGROUND Ice hockey has one of the highest sport participation and injury rates in youth in Canada. Body checking (BC) is the predominant mechanism of injury in leagues in which it is permitted. The objectives of this study were to determine whether the incidence and types of physical contact differ for Bantam players (aged 13-14 years) who were exposed to BC at Pee Wee level (aged 11-12 year...

undreds of microRNAs are encoded in animal genomes, yet the function of only two were known until recently. That number has now doubled with the identification of two miRNAs, mir14 and bantam , both of which appear to regulate cell death in Drosophila , according to reports from Peizhang Xu, Bruce Hay (California Institute of Technology, Pasadena, CA), and colleagues and from Julius Brennecke, ...

undreds of microRNAs are encoded in animal genomes, yet the function of only two were known until recently. That number has now doubled with the identification of two miRNAs, mir14 and bantam , both of which appear to regulate cell death in Drosophila , according to reports from Peizhang Xu, Bruce Hay (California Institute of Technology, Pasadena, CA), and colleagues and from Julius Brennecke, ...

During the development of multicellular organisms, body growth is controlled at the scale of the organism by the activity of long-range signaling molecules, mostly hormones. These systemic factors coordinate growth between developing tissues and act as relays to adjust body growth in response to environmental changes [1]. In target organs, long-range signals act in concert with tissue-autonomou...