0

clinical and histopathological features of basal cell carcinoma (bcc) may differ according to the type of carcinogen involved. bcc arising from radiotherapy treatment has high incidence and its clinical and histopathological features may be different from bccs caused by other carcinogens. the aim of our study was to investigate any possible association between specific histopathological or clin...

0

background : basal cell carcinoma is the most common form of skin cancer in men. increased marker expressions of apoptosis and cell proliferation have been found in the majority of basal cell carcinomas. our purpose was to determine whether any correlation between immunohistochemical expressions of p53 and ki-67 in different histopathological variants of basal cell carcinoma and patient’s age, ...

0

nevoid basal cell carcinoma syndrome (bcns) is an autosomal dominant inherited disorder. multiple organ systems may be affected in this syndrome including abnormalities of the skin, skeletal system, genitourinary system and central nevus system. in this report, we present a case of nevoid basal cell carcinoma syndrome in a 26-year-old male patient. the patient had multiple odontogenic keratocys...

there is an impression that basal cell carcinomas (bcc) occurring in younger population may be of more invasive behavior in comparison to those arising in older patients. the purpose of this study was to investigate this hypothesis by comparing the histological types of bcc in a large cohort of young and old patients. a total of 287 histological reports and clinical records were evaluated. a co...

background and objective: clinical behavior of basal cell carcinoma (bcc) is known to be different according to histological growth pattern and basosquamous cell carcinomas (bsc) are known with their aggressive behavior and metastatic capacity. in this study, we evaluated bcl-2 and cyclin d1 expressions in bcc and bsc cases comparatively, to explore their predictive value on the aggressive beha...

Background: The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or to induce apoptosis. However, when mutated, p53 is no longer able to properly accomplish these functions. The aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

nevoid basal cell carcinoma syndrome (nbccs), also known as gorlin syndrome, is a hereditary condition characterized by a wide range of developmental abnormalities and a predisposition to neoplasms . the estimated prevalence varies from 1/57,000 to 1/256,000, with a male-to-female ratio of 1:1. main clinical manifestations include multiple basal cell carcinomas (bccs), odontogenic keratocysts o...