نتایج جستجو برای: batch study

تعداد نتایج: 3989323  

2016
E Burmeister Getz KJ Carroll B Jones LZ Benet

Current pharmacokinetic (PK) bioequivalence guidelines do not account for batch-to-batch variability in study design or analysis. Here we evaluate the magnitude of batch-to-batch PK variability for Advair Diskus 100/50. Single doses of fluticasone propionate and salmeterol combinations were administered by oral inhalation to healthy subjects in a randomized clinical crossover study comparing th...

Journal: :journal of optimization in industrial engineering 2010
mir bahadorgholi aryanezhad mehdi karimi nasab sudabeh bakhshi

batch sizing in different planning period is categorized as a classical problem in production planning, that so many exact & heuristic methods have been proposed to solve this problem, each of which considering various aspects of the original problem. the solution obtained from majority – e.g. mrp – is in this format that there may be some periods of idleness or each period should produ...

2016
Christian Müller Arne Schillert Caroline Röthemeier David-Alexandre Trégouët Carole Proust Harald Binder Norbert Pfeiffer Manfred Beutel Karl J. Lackner Renate B. Schnabel Laurence Tiret Philipp S. Wild Stefan Blankenberg Tanja Zeller Andreas Ziegler

Technical variation plays an important role in microarray-based gene expression studies, and batch effects explain a large proportion of this noise. It is therefore mandatory to eliminate technical variation while maintaining biological variability. Several strategies have been proposed for the removal of batch effects, although they have not been evaluated in large-scale longitudinal gene expr...

2012
Sabyasachi Karati Abhijit Das Dipanwita Roy Chowdhury Bhargav Bellur Debojyoti Bhattacharya Aravind Iyer

In this paper, we study several algorithms for batch verification of ECDSA signatures. The first of these algorithms is based upon the naive idea of taking square roots in the underlying field. We also propose two new and efficient algorithms which replace square-root computations by symbolic manipulations. Experiments carried out on NIST prime curves demonstrate a maximum speedup of above six ...

2014
Mingjie Chen R Shyama Prasad Rao Yiming Zhang Cathy Xiaoyan Zhong Jay J Thelen

The goal of metabolomics data pre-processing is to eliminate systematic variation, such that biologically-related metabolite signatures are detected by statistical pattern recognition. Although several methods have been developed to tackle the issue of batch-to-batch variation, each method has its advantages and disadvantages. In this study, we used a reference sample as a normalization standar...

2013
Devang Upadhyay

The present study deals with the batch and fed-batch mass production of Steinernema carpocapsae. S. carpocapsae is an entomoparasitic nematode that is used as a biological control agent of soil-borne crop insect pests. The ability and efficiency of fed-batch culture process was successful through the utilization of the nematode’s bacterial symbiont Xenorhabdus nematophila. Results from the fed-...

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