the biobreeding- diabetes prone (bb-dp) rat spontaneously develops an autoimmune diabetic syndrome that is dependent on the rt1 u major histocompatibility complex (mhc) haplotype and homozygosity for an allele at the lymphopenia (lyp) locus. lyp mutation is responsible for a peripheral t -lymphopenia. there are other genetic loci contributing to diabetes susceptibility in this strain. bb rats c...

Two stages gas guns are used for various purposes, particularly for mechanical characterization of materials at high rate of deformations. The performance of a two stages gas gun is studied in this work using the theory of the two-stage gas gun proposed by Rajesh, numerical simulation using combined Eulerian/ Lagrangian elements in Autodyna commercial code and experiment using a two stage gas g...

Eye injuries resulting from ocular trauma pose a frequent threat to vision the world over. The setting and causes of eye injury are diverse, but previous studies have demonstrated that the risk and type of injury is often correlated with age, gender, and race. While a focused history and prompt ocular examination are essential to immediate management, patient education regarding safety precauti...

IMPORTANCE Gun violence and injuries pose a substantial threat to children and youth in the United States. Existing evidence points to the need for interventions and policies for keeping guns out of the hands of children and youth. OBJECTIVES (1) To examine the association between state gun law environment and youth gun carrying in the United States, and (2) to determine whether adult gun own...