endothelial cells present in brain are unique and differ from other peripheral tissues in a number of ways, which ensures specific brain endothelial barrier properties. endothelial dysfunction is the earliest event in the initiation of vascular damage caused by inflammation. various micrornas (mirna) have been discovered in different cellular components of the blood bran barrier (bbb). mirnas a...

Because of the isomorphism ${C \kern -0.1em \ell}_{1,3}(\Bbb{C})\cong{C \ell}_{2,3}(\Bbb{R})$, it is possible to complexify spacetime Clifford algebra \ell}_{1,3}(\Bbb{R})$ by adding one additional timelike dimension Minkowski spacetime. In a recent work we showed how this treatment provide particular interpretation Dirac particles and antiparticles in terms new temporal dimension. article thor...

In this article, we give several generalizations of the concept of annihilating ideal graph over a commutative ring with identity to modules. Weobserve that over a commutative ring $R$, $Bbb{AG}_*(_RM)$ isconnected and diam$Bbb{AG}_*(_RM)leq 3$. Moreover, if $Bbb{AG}_*(_RM)$ contains a cycle, then $mbox{gr}Bbb{AG}_*(_RM)leq 4$. Also for an $R$-module $M$ with$Bbb{A}_*(M)neq S(M)setminus {0}$, $...

The blood-brain barrier (BBB) restricts the entry of circulating drugs and xenobiotics into the brain, and thus its permeability to substances is a critical factor that determines their central effects. The infant brain is vulnerable to neurotoxic substances partly due to the immature BBB. The employment of in vitro BBB models to evaluate permeability of compounds provides higher throughput tha...

blood brain barrier (bbb) is a specialized non fenestrate barrier that formation by the endothelial cells and controls the transportation of the cells and molecules in to the brain. reducing in function of bbb is one of disruptions in neurological diseases like multiple sclerosis. endothelial progenitor cell (epc) help to the bbb to control the diapedesis of inflammatory cells & molecules in to...