We have prepared and studied a family of cyanobiphenyl dimers with varying linking groups with a view to exploring how molecular structure dictates the stability of the nematic and twist-bend nematic mesophases. Using molecular modelling and 1D 1H NOESY NMR spectroscopy, we determine the angle between the two aromatic core units for each dimer and find a strong dependency of the stability of bo...

The mechanism by which sequence non-specific DNA-binding proteins enhance DNA flexibility is studied by examining complexes of double-stranded DNA with the high mobility group type B proteins HMGB2 (Box A) and HMGB1 (Box A+B) using atomic force microscopy. DNA end-to-end distances and local DNA bend angle distributions are analyzed for protein complexes deposited on a mica surface. For HMGB2 (B...

Asymmetrical bending waves can be obtained by reactivating demembranated sea urchin spermatozoa at high Ca2+ concentrations. Moving-film flash photography shows that asymmetrical flagellar bending waves are associated with premature termination of the growth of the bends in one direction (the reverse bends) while the bends in the opposite direction (the principal bends) grow for one full beat c...

bendway weirs are an important tool in multi-purpose erosion control and are implemented to control erosion, restore streams, and improve habitat. these structures create a hydraulic effect that reduces erosion on the outer bank of a bend by reducing flow velocities near the outer bank and reduce the concentration of currents on the outer bank creating better current alignment through the bend....

Type IIA topoisomerases modify DNA topology by passing one segment of duplex DNA (transfer or T-segment) through a transient double-strand break in a second segment of DNA (gate or G-segment) in an ATP-dependent reaction. Type IIA topoisomerases decatenate, unknot and relax supercoiled DNA to levels below equilibrium, resulting in global topology simplification. The mechanism underlying this no...

An expression for the fraction of incident radiation transmitted by a right angle bend in a rectangular light pipe is derived. This expression is used to show that, in a planar light pipe structure with right angle bends, light attenuation is due only to reflection losses at the walls if the launching angle is 45 degrees .

The centromere complex is a multicomponent structure essential for faithful chromosome transmission. Here we show that the S. cerevisiae centromere protein Cpf1 bends centromere DNA element I (CDEI) with the bend angle ranging from 66 degrees to 71 degrees. CDEI DNA sequences that carry point mutations which lead to reduced Cpf1 binding affinity and in vivo centromere activity are still able to...

Using the analytic estimates developed for the emittance diagnostic channel for the nal-stage cooling experiment, we conclude that diagnostics for both an initial-stage cooling experiment, and for the targetry experiment could be performed with a bent solenoid of 1.25 T eld strength. The solenoid bore would need to be at least 40 cm for either study. The targetry study is less demanding in accu...

Many proteins interact with and deform double-stranded DNA in cells. Single-molecule experiments have studied the elasticity of DNA with helix-deforming proteins, including proteins that bend DNA. These experiments increase the need for theories of DNA elasticity which include helix-deforming proteins. Previous theoretical work on bent DNA has examined a long DNA molecule with many nonspecifica...