Ehlers Danlos syndrome (EDS) is an inherited connective tissue disease due to impaired collagen metabolism. Joint hypermobility and skin hyper extensibility are the major findings. Six types of EDS are recognized. Type I or Gravis type is characterized by skin hyperextensibility, joint hypermobility, skin splitting autosoml dominancy inheritance, preterm premature rupture of membrane (PPROM) an...

background: benign joint hypermobility syndrome (bjhs) is a disorder due to laxity of supporting connective tissue of joints. inguinal hernia is also proposed due to weak supporting tissue that may be a clinical presentation of a more widespread problem of connective tissue. materials and methods: in a cross-sectional study, prevalence of benign hypermobility joint syndrome (bhjs) was assessed ...

The distinction between the Ehlers-Danlos syndrome hypermobile type (EDSH) and the benign joint hypermobility syndrome (BJHS) is unclear. The aim of the present study was to compare skin ultrastructural abnormalities of EDSH and BJHS among different families. Skin of 23 EDSH, 27 BJHS, and 41 asymptomatic subjects from 17 families was examined using transmission electron microscopy. Similar ultr...

Methods Sixty-three children with benign joint hypermobility syndrome were included in case group and 63 without any rheumatologic disease were placed in control group. We used Carter-Wilkinson and Beighton criteria for diagnosing of benign joint hypermobility syndrome. MVP was evaluated by echocardiography in both groups. The mitral leaflet displacement >2 mm considered as cut off for diagnosi...

hyper ige syndrome (hies) is a rare primary immunodeficiency disease. most of hies cases are sporadic. hies type ad is caused by mutation in signal transducer and activator of transcription-3 (stat-3). a number of mosaicism hies has been reported that is associated with intermediate phenotype. autosomal recessive hies (ar-hies) is due to mutation in dock-8 or cytokine sis 8 and tyk2 or tyrosine...

Background & Objective:  Hyper- kyphosis negatively affects health status, physical mobility, and quality of life. Corrective exercise interventions are often utilized to manage subjects with thoracic hyper-hypnosis. The purpose of this study was to investigate the effectiveness of multimodal spine strengthening exercises (spinal strengthening, spinal alignment and other such exercises for incr...

Hypermobility denotes an increased range of joint movements and is the result of ligamentous and joint capsule laxity. Benign joint hypermobility syndrome is hypermobility associated with symptoms--arthralgia, myalgia, fatigue, anxiety and fibromyalgia. Clinical manifestations of benign joint hypermobility syndrome include almost all organic systems, and reflect the ubiquity of connective tissu...