Abstract Polycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants (POPs) that widely distributed in the environment and cause significant environmental damage. Furthermore, they endanger human health by polluting food from natural processing. Therefore, it is necessary to accurately detect PAHs various sample matrices, which requires precise, practical, rapid detection methods....

Solution-processable [1]benzothieno[3,2-b]benzothiophene (BTBT) derivatives with various end-capping groups, 2-(phenylethynyl)benzo[b]benzo[4,5]thieno[2,3-d]thiophene (Compound 1), 2-octyl-7-(5-(phenylethynyl)thiophen-2-yl)benzo[b]benzo[4,5]thieno[2,3-d]thiophene 2), and triisopropyl((5-(7-octylbenzo[b]benzo[4,5]thieno[2,3-d]thiophen-2-yl)thiophen-2-yl)ethynyl)silane 3), have been synthesized c...

The mutagenic activities of benzo[f]quinoline, benzo[h]quinoline, and a number of their derivatives, including dihydrodiols, K-region oxides, diol epoxides, and tetrahydroepoxides, were assessed in strain TA 100 of Salmonella typhimurium. The dihydrodiol derivatives of benzo[f]quinoline and benzo[h]quinoline were also tested for tumorigenic activity in newborn mice. Benzo[f]quinoline was metabo...

background: residents of the northeastern region of iran experience high mortality rates from esophageal squamous cell carcinoma (escc). one etiologic factor might be exposure to high levels of polycyclic aromatic hydrocarbons, including benzo(|î±|)pyrene (bî±p). we examined whether food or water are the major sources of bî±p exposure in this population. materials and methods: we used a dietary...

Concentration levels of 16 polycyclic aromatic hydrocarbons (PAHs) consisting of naphthalene, acenaphthylene, acenaphthene, fluorine, phenantherene, anthracene, fluor?anthene, pyrene, benzo(a)anthracene, chrysene, benzo(b)fluoranthene, benzo(k)fluoranthene, benzo(a)p?yrene, dibenzo(a,h)ant?hracene, indeno(1,2,3-cd) pyrene and benzo(g,h,i)perylene were measured in water and sediment samples col...

polynuclear Aromatic Bydromrbons As criteria for the presence of polynuclear aromatic hydrocarbons in tobacco smoke, the list of J. W. Cook (m) has been widely accepted by tobacco chemists. The Surgeon General’s 1964 Report and Cook’s paper are in agreement with respect to the presence of benzo(a)pyrene (3 : 4benzopyrene) , dibenz (a,h) -anthracene (12 : 5,6-dibenzanthrac) : benzo(c) phenanthre...

In vitro studies have previously indicated that benzo(a)pyrene distributes primarily into the plasma lipoprotein fraction when incubated with whole plasma. Hydroxylated metabolites of benzo(a)pyrene distribute increasingly into the albumin fraction as the degree of metabolite hydroxylation increases. This report assesses the influence of plasma lipoproteins and albumin as carriers for benzo(a)p...

The binding of [3H]benzo(a)pyrene to proteins of rat liver cytosol, the nuclear uptake of cytosolic protein-bound [3H]-benzo(a)pyrene, and the subsequent nuclear metabolism of the polycyclic hydrocarbon were investigated. The binding of [3H]benzo(a)pyrene to cytosol had a saturable high affinity component with a Kd of 2.54 nM and a capacity of 530 fmol/mg protein. Specific binding of [3H]benzo(...

1. Unsubstituted 6-membered aromatic ring systems (fused, unfused, or mixed) chrysene mutagenic initiator carcinogenic pyrene co-carcinogen mutagenic benzo[a]pyrene mutagenic carcinogenic fetotoxic teratogenic benzo[e]pyrene carcinogenic mutagenic benzo[a]anthracene mutagenic carcinogenic benzo[c]phenanthrene initiator mutagenic naphthalene inhibitor phenanthrene initiator mutagenic anthracene ...

A pathway for the biotransformation of the environmental pollutant and high-molecular weight polycyclic aromatic hydrocarbon (PAH) benzo[k]fluoranthene by a soil bacterium was constructed through analyses of results from liquid chromatography negative electrospray ionization tandem mass spectrometry (LC/ESI(-)-MS/MS). Exposure of Sphingobium sp. strain KK22 to benzo[k]fluoranthene resulted in t...