BACKGROUND Antenatal steroids are standard of care for women who are at risk of preterm delivery; however, antenatal steroid dosing and formulation have not been evaluated adequately. The standard clinical 2-dose treatment with betamethasone-acetate+betamethasone-phosphate is more effective than 2 doses of betamethasone-phosphate for the induction of lung maturation in preterm fetal sheep. We h...

The objective of this study was to investigate the effects of saffron as a natural sunscreen and moisturizer. The pollens of the saffron were dried and powdered in a grinder. The experimental formulations included a homosalate (8%) lotion reference, lotions with 2, 4 and 8% of grinded saffron, and the control lotion base without saffron. The lotions containing saffron were prepared like homosal...

To determine the effect of Artemisia sieberi lotion in signs & symptoms of Tinea versicolor, a randomized, double - blind clinical trial was performed comparing topical application of Artemisia sieberi lotion with Clotrimazole topical lotion, twice daily for 2 week. 60 patients suffering from Tinea versicolor completed the study. 29 patients were treated with Artemisia sieberi lotion and 31 pat...

A simultaneous approach to address optimal product and process design is presented and applied to a cosmetic lotion case study. The problem formulation integrates product quality, as assessed by customers, a model predicting lotion viscosity as a function of its composition and a process model linking process design and operation with lotion composition and microstructure. The solution of such ...

BACKGROUND Betamethasone is used for its antiinflammatory and immunosuppressive effects in disorders of many organ systems. However, the pharmacokinetic properties of betamethasone in plasma after intramuscular injection of betamethasone sodium phosphate and betamethasone acetate dual-acting suspension need further investigation. OBJECTIVES The main aim of this study was to determine the phar...

BACKGROUND Central nervous system injuries after transforaminal epidural steroid injections have been ascribed to occlusion of the blood vessels supplying the spinal cord and brain by the particulate steroid. METHODS The authors compared the sizes of the particles of the steroids methylprednisolone acetate, triamcinolone acetonide, dexamethasone sodium phosphate, betamethasone sodium phosphat...

The effect of pH, media, phosphate concentration and ionic strength on the kinetics of thermal degradation of betamethasone valerate and betamethasone dipropionate has been investigated. A validated HPLC method has been used to determine the parent compounds and their major thermal degradation products identified in the reaction. Betamethasone-17-valerate gave rise to two major products, namely...

To determine the effect of Artemisia sieberi lotion in signs & symptoms of Tinea versicolor, a randomized, double - blind clinical trial was performed comparing topical application of Artemisia sieberi lotion with Clotrimazole topical lotion, twice daily for 2 week. 60 patients suffering from Tinea versicolor completed the study. 29 patients were treated with Artemisia sieberi lotion and 31 pat...

background and objective: preterm birth is a public health problem and late preterm birth (deliveries between 34-36 weeks of gestation) accounts for 75% of all preterm births. antenatal betamethasone can reduce the severity of respiratory distress in preterm infants and its effect is accepted in 24-34 weeks of gestation. our goal was to determine the neonatal outcomes of betamethasone prescript...