Biliary ascariasis is a common disease in certain geographical areas of the world. The adult form of the worm usually lives in the human intestine. Biliary complications due to ascaris infestation are uncommon but are becoming an important clinical problem, as fatal cases have been reported in the literature. Many authors have recommended traditional surgical treatment for removal of the w...

biliary atresia is characterized by the progressive obliteration of extra- and intrahepatic biliary duct system leading to the obstruction of bile flow in infancy. the cause(s) of biliary atresia remain unclear and many surgical options for bypassing the atretic segment have been described. 1-3 biliary atresia may be associated with small bowel atresia.  the surgical interventions for biliary d...

background : most diagnostic tests for biliary atresia (ba) are invasive. this study evaluates the sensitivity and specificity of serum  tumor necrosis factor-α (tnf-α) for diagnosing extra hepatic biliary duct atresia (ehba) in infants. materials and methods : infants with cholestasis who were admitted to children′s medical center hospital were evaluated. a total of 50 infants (20 with ehba an...

background liver cirrhosis is one of the major causes of hospitalization and mortality in children. a wide spectrum of disorders including developmental abnormali­ties, infections, metabolic and genetic disorders can lead to liver cirrhosis in pediatric patients. determination of its etiology is important for treatment mo­dality, prevention of progressive liver damage, family counseling and pri...

results hla-drb1*07 (rr 5.3, p = 0.0008) and hla-drb1*08 (rr n.c. p = 0.0005) were significantly associated with the risk of pbc development. patients younger than 45 years had significantly higher alanine aminotransferase (p = 0.038) and alkaline phosphatase levels (p = 0.047) than older cases. in comparison to non-cc rs12979860, patients with cc rs12979860 genotype showed an early histologica...

conclusions co-occurrence of pbc with wd is rare, which can cause diffusely intrahepatic copper deposition. early liver biopsy and genetic testing are necessary for the diagnosis. the combination of ursodeoxycholic acid with zinc and sodium dimercaptopropane sulfonate is effective. introduction both primary biliary cirrhosis (pbc) and wilson’s disease (wd) can cause copper retention in the live...

chronic liver diseases in children is the result of many different diseases including: metabolic, genetic, infectious, toxic and idiopathic causes. this was a case series study on 133 infants and children with age range 6 month to 12 years old, who presented clinically with manifestation of chronic liver disease and were admitted to children hospital medical center from year 1999 to 2000. in th...

a 63-year-old woman suffering from progressive systemic sclerosis for about 20 years disclosed symptoms of liver disease within the last three years. diagnosis of biliary cirrhosis was established on the basis of clinical picture, pathological examination of the hepatic tissue sample, immunological tests, and x-ray studies. association of systemic sclerosis with primary biliary cirrhosis is bri...

background: biliary atresia is a 100% fatal disorder without any treatment in infants as a leading cause of cirrhosis and kasai operation, as the only operative choice, which plays a crucial role in increasing their rate of survival. nonetheless, many patients end up with liver transplantation in the future owing to various inevitable hepatic and biliary problems which do remain after the kasai...

introduction percutaneous nephrolithotomy is generally considered a safe option for the management of large complex or infectious upper urinary tract calculi. biliary tract injury is a rare and potentially serious complication of percutaneous nephrolithotomy that can even lead to mortality, especially in cases where biliary peritonitis develops. all reported cases of biliary tract injury have b...