BACKGROUND This review provides the physician with a clinical approach to the diagnosis and management of spider bites. It examines the recent literature concerning management of bites causing dermonecrosis, secondary infection, neuromuscular damage, and allergic reactions. METHODS Using the key words "spider bites," "brown recluse spider bites," "necrotic arachnidism," "black widow spider bi...

Eggs of black widow spiders in the genus Latrodectus Walckenaer, 1805 (Theridiidae) are known to be toxic when injected into mammals. We surveyed eggs from 39 species of spiders in 21 families to determine if spider egg toxicity is a unique property of widow spiders, or if spider egg toxicity is associated with other spider taxa. Eggs from 13 species of spiders in three families were determined...

Black widow spiders (members of the genus Latrodectus) are widely feared because of their potent neurotoxic venom. α-Latrotoxin is the vertebrate-specific toxin responsible for the dramatic effects of black widow envenomation. The evolution of this toxin is enigmatic because only two α-latrotoxin sequences are known. In this study, ~4 kb α-latrotoxin sequences and their homologs were characteri...

This article is a case study of a patient cared for in the hours before her death. After the patient's death, we learned the patient died of a black widow spider bite. This article sheds light on the potential seriousness of this venom and allows for more rapid detection and treatment of those who are unfortunate enough to be bitten. The authors have documented the sequence of events for the pa...

Black widow spiders can cause variable clinical scenarios from local damage to very serious conditions including death. Acute myocardial damage is rarely observed and its prognostic significance is not known. We report a rare case of a 35-year-old man who developed an acute myocarditis with cardiogenic pulmonary edema requiring mechanical ventilation caused by black widow spider's envenomation....