Hemostasis is critical for adequate anatomical visualization during endoscopic endonasal skull base surgery. Reduction of intraoperative bleeding should be considered during the treatment planning and continued throughout the perioperative period. Preoperative preparations include the optimization of comorbidities and cessation of drugs that may inhibit coagulation. Intraoperative consideration...

BACKGROUND Elderly patients have more special medical needs when compared with young ones; thus, the results of open reduction and internal fixation (ORIF) for acetabular fractures should be stratified by age in these patients. This study seeks to determine whether the age of the patient influences the results of the ORIF for acetabular fractures. METHODS We performed a retrospective analysis...

Background:Upper gastrointestinal (GI) bleeding remains a problem in critically ill-newborns. The use of H2 blockers, by maintaining gastric pH ³ 4, reduces the risk of stress-ulceration and gastric hemorrhage. This study therefore, has evaluated the effects of short-term prophylactic‎ ranitidine in controlling gastric pH and prevention of GI bleeding in neonates. Methods: This randomized contr...

Atrial fibrillation is a common arrhythmia that increases the risk of stroke and systemic embolism. Warfarin is a highly effective treatment in reducing this risk, but a narrow therapeutic range, drug and food interactions, required monitoring, and bleeding limit its use. We review Apixaban, an oral inhibitor of Factor Xa, which has been shown in large randomized trials to have superior efficac...

Introduction:Bleeding is a common concern during functional endoscopic sinus surgery (FESS) that can increase the risk of damage to adjacent vital elements by reducing the surgeon’s field of view. This study aimed to explore the efficacy of topical tranexamic acid in reducing intraoperative bleeding. Materials and Methods:This double-blind, randomized clinical trial was conducted in 60 patients...

Bleeding is the most common complication after percutaneous coronary intervention (PCI) and has been shown to be a very significant adverse prognostic event, increasing short-term and longterm adverse outcomes. Access-site bleeding accounts for the majority of these hemorrhagic complications. Transradial access is associated with a very sizeable reduction in access-site-related bleeding. Patien...