Mineralization is an essential requirement for normal skeletal development, but under certain pathological conditions organs like articular cartilage and cardiovascular tissue are prone to unwanted mineralization. Recent findings suggest that the mechanisms regulating skeletal mineralization may be similar to those regulating pathological mineralization. In general, three forms of cell-mediated...

In this study, the zonality method has been used to separate geochemical anomalies and calculate erosional levels in regional scale for porphyry-Cu deposit, Abrisham-Rud (Semnan province, East of Iran). maps multiplicative haloes, co-existence both supra-ore elements sub-ore local maxima implied blind mineralization northwest study area. Moreover, considering calculated indices two previously p...

Extracellular matrix (ECM) mineralization is a physiological process in bone and a pathological one in soft tissues. The mechanisms determining the spatial restriction of ECM mineralization to bone physiologically are poorly understood. Here we show that a normal extracellular phosphate concentration is required for bone mineralization, while lowering this concentration prevents mineralization ...

Defective bone mineralization has serious clinical manifestations, including deformities and fractures, but the regulation of this extracellular process is not fully understood. We have developed a mathematical model consisting of ordinary differential equations that describe collagen maturation, production and degradation of inhibitors, and mineral nucleation and growth. We examined the roles ...

Discrimination of the blind and dispersed mineralization deposits is a challenging problem in geochemical exploration. The frequency domain (FD) of the surface geochemical data can solve this important issue. This new exploratory information can be achieved using the interpretation of FD of geochemical data, which is impossible in spatial domain. In this research work, FD of the surface geochem...

Mineralization of fibrillar collagen with biomimetic process-directing agents has enabled scientists to gain insight into the potential mechanisms involved in intrafibrillar mineralization. Here, by using polycation- and polyanion-directed intrafibrillar mineralization, we challenge the popular paradigm that electrostatic attraction is solely responsible for polyelectrolyte-directed intrafibril...

Mineralization potentials, rates, and kinetics of the three phenoxy acid (PA) herbicides, 2,4-dichlorophenoxyacetic acid (2,4-D), 4-chloro-2-methylphenoxyacetic acid (MCPA), and 2-(4-chloro-2-methylphenoxy)propanoic acid (MCPP), were investigated and compared in 15 soils collected from five continents. The mineralization patterns were fitted by zero/linear or exponential growth forms of the thr...

the infomax algorithm is a popular method in blind source separation problem. in this article an extension of the infomax algorithm is proposed that is able to separate mixed signals with any sub- or super-gaussian distributions. this ability is the results of using two different nonlinear functions and new coefficients in the learning rule. in this paper we show how we can use the distribution...

Osteoblastic mineralization occurs during the early stages of bone formation. During this mineralization, hydroxyapatite (HA), a major component of bone, is synthesized, generating hard tissue. Many of the mechanisms driving biomineralization remain unclear because the traditional biochemical assays used to investigate them are destructive techniques incompatible with viable cells. To determine...

maherabad prospect area, which is studied in detail, is the first porphyry cu-au mineralization in the east of iran. based on relation of mineralization with subvolcanic intrusive bodies mostly monzonitic with porphyry texture, extent and types of alteration including potassic, sericitic- potassic, quartz- sericite- carbonate- pyrite, quartz- carbonate- pyrite, silicification- propylitic, propy...