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background: celiac disease (cd) is a small bowel enteropathy caused by permanent wheat gluten intolerance. one of the earliest signs of the mucosal immune activation in cd is an increase in the intestinal intraepithelial lymphocytes (iiels) count in the small intestinal epithelium. although most of those iiels express ??tcr, cd is characterized by an increase in the gdtcr + iiels. objective: th...

purpose: to compare ophthalmic artery velocity in eyes with nonarteritic anterior ischemic optic neuropathy (naion) with that of normal fellow eyes. methods: in this case-control study, 20 patients with unilateral naion and disease onset less than 8 weeks, were enrolled. using color doppler imaging, mean, maximum systolic and end diastolic ophthalmic artery velocities were evaluated. the result...

background: human peripheral blood nk cells constitutively express cd56 and cd16 antigens. peripheral blood nk cells seem to be strongly related with decidual nk cells, and may reflect the decidual nk cell functional status. there are varied reports concerning the relationship between nk cell cytotoxicity in women with recurrent spontaneous abortion. objective: to study nk activity in women wit...

alzheimer's disease (ad) is considered as the greatest thread to adults aged 65 and older. it stands as the most common cause of dementia, the prevalence of which is around 24 million worldwide. ad is a progressive and degenerative disorder that combats the neurons, leading to impairment of different cognitive functions. ad is characterized by an accumulation of two factors normally presen...

background: the mechanisms underlying cerebral hypercapnic vasodilatation are not fully understood.   objective: to investigate the role of nitric oxide (no) and atp-sensitive potassium (k atp ) channels in basal blood flow regulation and hypercapnia-induced vasodilatation in rabbit cerebral blood vessels.   methods: the change in cerebral blood flow was measured by a laser doppler flowmeter in...

the mechanisms underlying cerebral vasodilatation during hypercapnia are not fully understood. to examine the role of nerves and prostaglandins in the regulation of basal blood flow and in hypercapnia-induced vasodilatation in the cerebral blood vessels of rabbit. cerebral blood flow was measured by laser doppler flow-meter in 18 nzw rabbits anesthetized with sodium pentobarbital.  tetrodetoxin...

introduction: the relation between morphine and nitric oxide release has been shown. due to important role of nitric oxide in regulation of skin blood flow, the aim of this study was to investigate the effect of nitric oxide synthase inhibitor (l-name) and nitric oxide synthesis precursor (l-arginine) on skin blood flow of intact and morphine-dependent rats. methods: skin blood flow of hind paw...

objective(s): one applications of nanotechnology is in the area of medicine which is called nanomedicine. primary instruments in nanomedicine can help us to detect diseases and used for drug delivery to inaccessible areas of human tissues. an important issue in simulating the motion of nanoparticles is modeling blood flow as a newtonian or non-newtonian fluid. sometimes blood flow is simulated ...

Background: The mechanisms underlying cerebral hypercapnic vasodilatation are not fully understood. Objective: To investigate the role of nitric oxide (NO) and ATP-sensitive potassium (KATP) channels in basal blood flow regulation and hypercapnia-induced vasodilatation in rabbit cerebral blood vessels. Methods: The change in cerebral blood flow was measured by a laser Doppler flowmeter in 18 Ne...