psuedopeptide backbone composed of N-(2-aminoethyl) glycine units, and nucleobases are attached by methylene carbonyl linkers (Fig. 1). Since the binding of PNA to DNA inhibits transcription, the potential of PNA has been focused to target an antisense drug.1 Moreover, PNA-peptides hybridization and improvements of the PNA backbone unit were developed to form DNA-DNA-PNA triplexes with nonspeci...

The recent researches on the tracking of binary offset carrier (BOC) modulated signals have been studied focusing on resolving the ambiguity problem caused by the multiple side-peaks in BOC autocorrelation. In this paper, we propose a novel unambiguous BOC tracking scheme with an improved tracking performance by using partial-pulses of BOC signals. Firstly, we observe that a sub-carrier consist...

Unambiguous tracking for Binary Offset Carrier (BOC) modulated signals is an important requirement of modern Global Navigation Satellite System (GNSS) receivers. An unambiguous tracking method based on combined correlation functions for even/odd order sine/cosine-BOC, Composite BOC (CBOC) and Alternate BOC (AltBOC) modulated signals is proposed. Firstly, a unified mathematical formulation for a...

Cdo and Boc encode cell surface Ig/fibronectin superfamily members linked to muscle differentiation. Data here indicate they are also targets and signaling components of the Sonic hedgehog (Shh) pathway. Although Cdo and Boc are generally negatively regulated by Hedgehog (HH) signaling, in the neural tube Cdo is expressed within the Shh-dependent floor plate while Boc expression lies within the...

OBJECTIVE To evaluate the effects of boceprevir (BOC) and telaprevir (TVR) on the pharmacokinetics (PK) of maraviroc (MVC) in healthy volunteers. METHODS In this open-label, fixed-sequence study, 14 volunteers received MVC 150 mg twice daily alone for 5 days (period 1), followed by MVC + BOC 800 mg 3 times daily and MVC + TVR 750 mg 3 times daily, each for 10 days in periods 2 and 3, respecti...

For unmanned aerial vehicles (UAVs), high-precision measurement and high-speed communication are necessary to realize flight operational missions. In this paper, we propose an integrated system in a Doppler frequency offset environment. The combines orthogonal division multiplexing (OFDM) modulation with binary carrier (BOC) formulate OFDM+BOC composite signal through power control. High-precis...

The inhibitory effect of boceprevir (BOC), an inhibitor of hepatitis C virus nonstructural protein 3 protease was evaluated in vitro against a panel of drug-metabolizing enzymes and transporters. BOC, a known substrate for cytochrome P450 (P450) CYP3A and aldoketoreductases, was a reversible time-dependent inhibitor (kinact = 0.12 minute, KI = 6.1 mM) of CYP3A4/5 but not an inhibitor of other m...

acetone fractionated peroxidase from crude extract of brassica oleracea leaves (cabbage) was purified in three steps on chromatographic columns, using sp-sepharose, deae-sepharose and con a-sepharose. the specific activity of purified main isoenzyme (boc-pod) is 1887 u/mg protein with rz: 3.1, which is 172 times more than the rz of crude extract with 4.3% recovery. the molecular weight of boc-p...

The Multiplexed Binary Offset Carrier (MBOC (6, 1)) signal is adopted to provide agreed [1], [2] common power spectral density for Galileo E1 Open Service (OS) and GPSIII L1C signals. In MBOC, a small amount of energy from a BOC signal with higher subcarrier frequency (i.e. BOC (6, 1)) is linearly added to the portions belong to the previous common baseline signal (i.e. BOC (1, 1)) to improve t...