background and aims. autogenous bone graft is commonly used for reconstruction of bone defects in routine surgical procedures. the complexity of producing bone grafts and their application has lead to the use of human bone matrix gelatin (hbmg). the present study was conducted to compare the efficacy of hbmg and autograft on the reconstruction of bone defects in rats. materials and methods. in ...

since bone marrow has been shown to contain osteoprogenitor cells, an experiment was devised to test its effects when injected percutaneously into osteotomies sites in rabbit radii. in this experimental study, the osteogenicity and its effect on early bone repair of bone marrow grafts were investigated. the purpose of this study was to determine whether bone marrow grafted percutaneously led to...

Objectives- To assess the ectopic bone formation in canine masseter muscle following the implantation of the natural bovine bone minerals (NBM) loaded with canine mesenchymal stem cells (MSCs).Design- Experimental study.Animals- four mongrel dogs.Procedures- Tripotent MSCs isolated from the canine bone marrow were loaded onto the NBM sponges and allowed to adhere. The cell-loaded scaffolds were...

Background: Repair of bone defects is challenging for reconstructive and orthopedic surgeons. In this study, we aimedto histomorphometrically assess new bone formation in tibial bone defects filled with octacalcium phosphate (OCP),bone matrix gelatin (BMG), and a combination of both.Methods: A total of 96 male Sprague Dawley rats aged 6-8 weeks weighing 120-150 g were randomly allocatedinto thr...

considering the importance of bone augmentation prior to implant placement in order to obtain adequate bone quality and quantity, many studies have been conducted to evaluate different techniques and materials regarding new bone formation. in this study, we investigated the bone healing capacity of two different materials deproteinized bovine bone mineral (dbbm with the trade name of bio-oss) a...

Objective- Bone regeneration is a multifactorial phenomenon which contributed to several factors. It is reported that risedronate is effective for musculoskeletal diseases. The current study was to determine effectiveness of the risedronate-loaded nano capsules for calvaria healing in rabbit.Design- Experimental study.Procedures- 15 white adult male New Zealand rabbits were used. Fo...

Background: Fluoride (F&minus) is a trace element that is incorporated into bone mineral during bone formation. This study assessed the effect of increasing Fluoride doses on the bone formation and microarchitecture on the Femur of rats by histological, and histometrical methods. Materials and Methods: A total of 16 rats was divided into one group of control and three groups of animals that re...