background: pancytopenia is a manifestation of a wide range of disorders. the main prognostic factor for predicting outcome and response to treatment is based on the underlying cause. to detect the root cause of this problem, depending on other accompanied signs or symptoms, the need for bone marrow examination and other advanced work ups is different at least at the practical level. this study...

Abstract All components of the musculoskeletal system can be involved by metabolic disorders as a result endocrine diseases, genetic alterations, and environmental or nutritional aspects, with important worldwide variations in prevalence severity. Early detection these is crucial because efficacy preventive measures availability treatments. The current chapter will focus on imaging appearance b...

The development of MR imaging has been a great advance in the imaging of bone marrow disorders. MR imaging exhibits excellent soft-tissue contrast and therefore has a greater sensitivity for marrow disease than did previously available modalities. This article reviews the normal morphology and appearance of bone marrow, describes the MR appearance of normal bone marrow, and discusses the MR fin...

Macrophage activation syndrome (MAS) is a rare feature of rheumatic disorders in children and adolescence and its presentation as the first symptom of rheumatic disorders is very infrequent. A 9-year-old girl, in whom MAS developed, was admitted to our Hospital in Tehran, Iran. She suffered from high grade fever and rash followed by multiple joint swelling months afterwards. Bone marrow aspira...

INTRODUCTION AND METHODS A bone marrow examination had been requested by the referring clinician in over half of the 250 patients referred to the haematology clinic at Konfo Anokye Teaching Hospital (KATH) between 1988 and 1998 for investigations for various haematological disorders. Although a full blood count and a peripheral blood film can go a long way to resolve some of these diagnostic ch...

objective(s):sea cucumber derived bioactive compound is considered efficient in treatment of bone disorders. this study was performed   to evaluate the effect of this extract on differentiation of rat bone marrow mesenchymal stem cells (rbmmsc) into osteogenic lineage. materials and methods: isolated rbmmsc were grown in dmem supplemented with 10% fbs. the cells were exposed to different concen...

background bone marrow transplantation (bmt)is nowadays used in various hematological disorders including leukemias. hemophilia a & b are sex linked bleeding disorders in which there are various genetic abnormalities in factor viii & ix genes. among various hematological disorders, bleeding disorders mainly hemophilia in now widely treated using plasma derived and recombinant factor viii & ix c...

Bone marrow transplantation (BMT) has emerged as a major therapeutic option for a number of nonmalignant disorders affecting the bone marrow and leading to clinical manifestations most likely affecting distant organs. Disorders such as autoimmune diseases, metabolic disorders, hemoglobinopathies, immunodeficiencies, and others have been the target of high-dose therapy and autologous or allogene...