background and purpose: invasive candidiasis (ic) is a significant cause of morbidity and mortality in patients with hematologic disorders and bone marrow transplant recipients. rapid, specific and sensitive test for the timely accuracy in immunocompromised patients to reduce mortality rates and prevent ic progress is necessary. we established a real-time pcr assay on blood for the diagnosis an...

Disseminated infection by Fusarium is a rare, frequently lethal condition in severely immunocompromised patients, including bone marrow transplant recipients. However, autologous bone marrow transplant recipients are not expected to be at high risk to develop fusariosis. We report a rare case of lethal disseminated Fusarium infection in an autologous bone marrow transplant recipient during pre-...

3. Han CS, Miller W, Haake R, Weisdorf D. Varicella zoster infection after bone marrow transplantation: incidence, risk factors and complications. Bone Marrow Transplant 1994; 13:277-83. 4. Koc Y, Miller KB, Schenkein DP, Griffith J, Akhtar M, DesJardin J, et al. Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome. Bi...

chio M, Porta F. Rapid regeneration of normally functional naive CD4+ T-cells after bone marrow transplantation from unrelated donors for combined immunodeficiency. Blood 1998; 92:3484-6. 7. Mackall CL, Hakim FT, Gress RE. T-cell regeneration: all repertoires are not created equal. Immunol Today 1997; 18:245-51. 8. Dickinson AM, Reid MM, Abinum M, et al. In vitro T cell depletion using Campath ...

Viral DNA was detected in 45.3% of the patients. Most patients tested positive for CMV (25.4%) or BK (21.2%). Although some differences frequency and type viruses were observed between bone marrow solid organ transplant, no association viral load, virus disease transplant adult pediatric recipients found. Analyzing all together, more frequently serum with symptoms complications.

"Fetal" erythrocytes are present in older children and certain adults with hematologic disorders. To determine if regenerating bone marrow produces such cells, we examined the blood of seven allogeneic bone marrow transplant recipients. Six patients were engrafted with donor cells, while on e patients recovered autologous bone marrow after rejection of a marrow transplant. All seven patients ha...

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington Research & Clinical Trials, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 3 Stem Cell Transplants, Dana-Farber Cancer Institute, Boston, Massachusetts Cancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada Bone Marrow Transplantation and Immune Deficiency, C...

Introduction: The thalassamias refer to a diverse group of hemoglobin disorders characterized by a reduced synthesis of  one or more of globin chains (α,β, γ, δβ,γδβ, δ and εγδβ).The main cure available today for thalassamia is bone marrow transplantation (BMT)  from compatible donor.On December 3, 1981 a 14-month-old child with β-thalassemia major recieved BMT from his HLA-identical sister in...

filgrastim-primed bone marrow versus filgrastim-mobilized peripheral blood stem cell transplantation in lymphoma patients. Blood 92:3489, 1998 7. Mandelam RK, Vento CA, Stiff PJ, Brott DA, Smith AK: Stem and progenitor cell content and ex vivo expansion potential of human bone marrow primed in vivo with G-CSF. Blood 90:344b, 1997 (abstr, suppl 1, part 2) 8. Martinez C, Urbano-Ispizua A, Rozman ...