Boron Neutron Capture Therapy (BNCT) can be performed at a facility with a nuclear reactor or at hospitals that have developed alternative neutron sources. A beam of epithermal neutrons penetrates the brain tissue, reaching the malignancy. Once there the epithermal neutrons slow down and these low-energy neutrons combine with boron 10 (delivered beforehand to the cancer cells by drugs or antibo...

The neutron irradiation system for boron neutron capture therapy (BNCT) using compact accelerators installed at hospitals was mainly investigated for the usage of direct neutrons from near-threshold Li(p,n)Be, and moderated neutrons from 2.5 MeV Li(p,n)Be reactions and other reactions. This kind of system can supply the medical doctors and patients with convenience to carry out BNCT in hospital...

Boron Neutron Capture Therapy (BNCT) [4, 5] is a form of a radiation therapy used for treatment of some kinds of cancer (mainly glioblastoma multiforme) which, due to their character, are hard to be extracted with surgical methods. The BNCT method involves the delivery of a capture compound − the B isotope is usually used – which preferentially concentrates in the cancer tissue, followed by the...

Boron Neutron Capture Therapy (BNCT) is a rather innovative cancer radiotherapy; at present it is object of increasing interest especially for treatment of those tumors where conventional therapy gives not satisfactory results (Glioblastoma and Malignant Melanoma). The therapy takes advantage of both chemical and physical aspects B: the possibility of selectively accumulating in tumor tissue th...

Boron neutron capture therapy (BNCT) is a binary treatment involving selective accumulation of boron carriers in a tumor followed by irradiation with a thermal or epithermal neutron beam. The neutron capture reaction with a boron-10 nucleus yields high linear energy transfer (LET) particles, alpha and (7)Li, with a range of 5 to 9 µm. These particles can only travel very short distances and rel...

Currently, nanostructured compounds have been standing out for their optical, mechanical, and chemical features and for the possibilities of manipulation and regulation of complex biological processes. One of these compounds is boron nitride nanotubes (BNNTs), which are a nanostructured material analog to carbon nanotubes, but formed of nitrogen and boron atoms. BNNTs present high thermal stabi...

Boron neutron capture therapy (BNCT) is a form of radiation therapy mediated by the short-range (less than 10 microns) energetic alpha (4He) and lithium-7 (7Li) ionizing particles that result from the prompt disintegration by slow neutrons of the stable (nonradioactive) nucleus boron-10 (10B). Recent advances in radiobiological and toxicological evaluation of tumour-affinitive boron-containing ...