Lactoferrin, a major whey protein of human milk, is considered as growth promoter for bifidobacteria, the predominant microorganisms of human intestine. In the present study, in vitro growth promotion and cell binding ability of bovine lactoferrin to several strains of Bifidobacterium longum have been demonstrated. A dose-dependent as well as strain-dependent growth promotion effect by lactofer...

Lactoferrin is an iron-binding protein present in external secretions and the secondary granules of neutrophils Its function is unknown, although immunomodulatory, antiinfective and nutritional roles have been proposed 11 I. Recently autoantibodies to lactofemn have been found as a component of anti-neutrophil cytoplasmic antibodies (ANCA) in patients with various autoimmune diseases 121. Why l...

s of the 7th International Conference on Lactoferrin / Résumés de la 7e Conférence internationale sur la lactoferrine N. Kumagai, S. Tsunematsu, H. Hamano, K. Yamauchi, and K. Tsuchimoto 385 Oral administration of lactoferrin enhances viral decline in patients with genotype-1B-related chronic hepatitis C treated with Peginterferon a-2B plus ribavirin T. Kuhara, K. Yamauchi, and M. Takase 385 Or...

An LC-MS/MS assay based on a signature peptide was developed and fully validated for the quantitation of bovine lactoferrin in infant formulas. Three unreported signature peptides were derived and identified from the tryptic peptides of bovine lactoferrin. The peptide ETTVFENLPEK was used for quantification based on assay performance. The blank matrix camel milk powder and bovine lactoferrin pr...

The existence of lactoferrin was first reported by S0rensen and S0rensen,' who observed a red protein fraction in human milk. The protein was first isolated by Groves2 from bovine and by Johansson3 from human milk, and subsequent studies showed that this protein (which has been variously called red milk protein, ekkrinosiderophilin, and lactotransferrin) is strikingly similar in many respects t...

Bovine herpesvirus 1 (BoHV-1) is widely distributed among cattle populations and has been associated with cells, fluids, and tissues collected from donor animals for use in reproductive technologies. The purpose of this study was to determine if lactoferrin would inhibit BoHV-1 in cell culture and to evaluate if embryos could develop normally when cultured in vitro with lactoferrin. In Experime...

The existence of lactoferrin was first reported by S0rensen and S0rensen,' who observed a red protein fraction in human milk. The protein was first isolated by Groves2 from bovine and by Johansson3 from human milk, and subsequent studies showed that this protein (which has been variously called red milk protein, ekkrinosiderophilin, and lactotransferrin) is strikingly similar in many respects t...

Bovine lactoferrin, a multifunctional glycoprotein, has been shown to strongly inhibit development of azoxymethane (AOM)-induced rat colon tumors. Little, however, is known about the inhibitory mechanisms. We have demonstrated recently that lactoferrin enhances the expression of a member of the tumor necrosis factor receptor family, Fas, in the colon mucosa during both early and late stages of ...

BACKGROUND Several randomized-controlled trials (RCTs) have sought to determine the efficacy of bovine lactoferrin in Helicobacter pylori eradication with equivocal results. AIM To evaluate the effect of bovine lactoferrin supplementation in H. pylori eradication. METHODS Electronic databases, reviews, bibliographies, abstracts and conference proceedings were searched. Included trials had t...

Human papillomavirus (HPV) cause common warts, laryngeal papilloma and genital condylomata and might lead to development of cervical cancer. Lactoferrin (LF) is a member of the transferrin family, which has antiviral activity against HPV-16. LF is an important player in the defense against pathogenic microorganisms and has also been shown to have activity against several viruses including herpe...