The measurements of Ra, Th and K using gamma spectrometry and radon concentration and exhalation rates measurements using solid state nuclear track (LR-115, Type-II plastic) detectors are used to asses a first order exposure risk for the persons residing in Fatehbad and Hissar districts of Western Haryana, India. The concentration of Radium, Thorium and Potassium in the soil samples varies from...

Current study concerns measurement of radioactivity levels in areas surrounding a 2420 MW thermal power plant fueled predominantly by bituminous coal. The concentrations of (226)Ra, (232)Th and (40)K in onsite bottom-ash were found to be 139 Bq/kg, 108 Bq/kg and 291 Bq/kg, respectively, the levels for these radiolnuclides in soil decreasing with distance from the power plant. At the plant perim...

Naturally occurring radioactive materials (NORMS) and fallout 137Cs were estimated in surface soils from the highly mineralized Singhbhum region of Eastern India. The activity concentrations varied from 50.67-109.14 Bq/kg (238U), 48.12142.55 Bq/kg (226Ra), 28.73-89.78 Bq/kg (232Th), 494.84-1121.36 Bq/kg (40K) and 1.8-7.48 Bq/kg (137Cs). Correlation between radionuclides was studied. 232Th/238U ...

The anti-malarial drug quinine and its quaternary derivative N-benzylquininium (BQ(+)) have been shown to inhibit gap junction (GJ) channels with specificity for Cx50 over its closely related homologue Cx46. Here, we examined the mechanism of BQ(+) action using undocked Cx46 and Cx50 hemichannels, which are more amenable to analyses at the single-channel level. We found that BQ(+) (300 µM-1 mM)...

In this study the endothelin (ET) receptors mediating contractions produced by ET-1, ET-3 and the selective ET(B) ligands sarafotoxin 6c (S6c) and BQ-3020 in guinea pig bronchus were investigated using SB 209670, a nonpeptide, mixed ET(A)/ET(B) receptor antagonist, and the peptide ET receptor antagonists BQ-123 (ET(A) receptor-selective), BQ-788 (ET(B) receptor-selective) and RES-701 (ET(B) rec...

The public concern for radioactivity of drinking-water has been increasing in recent years after the rapid development of nuclear power plants, and especially after the Fukushima nuclear accident. In this study, the radioactivity of water samples collected in the vicinity of nuclear facilities from seven provinces in China was measured and an average annual equivalent effective dose derived fro...

Temporal consequences of neurocompensation to balloon injury on endothelinergic functionality in rat contralateral carotid were evaluated. Rats underwent balloon injury in left carotid and were treated with CP-96345 (NK1 antagonist). Concentration-response curves for endothelin-1 were obtained in contralateral (right) carotid at 2, 8, 16, 30, or 45 days after surgery in the absence or presence ...

Introduction: This Study has was  carried out to measure and detect the natural occurred radionuclide content including 226Ra, 232Th and 40K in the  Nile River sediments at various locations in Upper Egypt, from Aswan to El-Minya. Additionally, we determine the absorbed dose rate, the annual effective dose equivalent, and excess lifetime cancer risk also has been calculated. Material and Metho...

Protein binding of hemoglobin (Hb) and bone marrow was used to compare in vivo reactions of 3 electrophilic metabolites of benzene, i.e., benzene oxide and 1,2- and 1,4-benzoquinone (1, 2-BQ and 1, 4-BQ), in F344 rats and B6C3F1 mice. Following a single p.o. administration of a mixture of [14C]- and [13C6]benzene between 50 and 400 mg/kg body weight, cysteine adducts of benzene oxide, 1,2-BQ, a...