Effects of intracerebroventricular (i.c.v.) treatment with atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) on the pressor response to i.c.v.-injected clonidine were investigated in conscious rats. I.c.v.-pretreatment with ANP (10 micrograms) or BNP (10 micrograms) inhibited the pressor response to i.c.v.-injected clonidine (10 micrograms). Systemic (i.v.) treatment with ANP...

introduction: the aim of this study was to evaluate the effects of aerobic exercise on brain natriuretic peptide (bnp) and c-reactive protein (crp) levels in women with cardiovascular diseases. materials and methods: in this semi experimental study, thirty female patients with at least one coronary artery stenosis (more than70%) were chosen and divided into two groups of aerobic training (n=15)...

Abbreviations: ACC/AHA, American College of Cardiology/American Heart Association; AF, atrial fibrillation; ANP, Atrial Natriuretic Peptide; AS, aortic stenosis; BNP, Brain Natriuretic Peptide; EF, ejection fraction; ESC, European Society of Cardiology; LA, left atrium; MR, mitral regurgitation; MS, mitral stenosis; MVA, mitral valve area; NT-Pro-BNP, N terminal-pro brain natriuretic peptide; P...

1. Introduction smaller fragments some of which may also have biological activity [5]. Less is known about the procession of BNP; it In the 20 years which have passed since the first is believed to be more constitutively expressed. Pro-brain description by de Bold of a natriuretic and diuretic natriuretic peptide is a 108-amino acid peptide also cleaved substance produced in the heart [1], a la...

In 1988 Sudoh and colleagues described a novel natriuretic peptide in porcine brain -brain natriuretic peptide(Sudoh et al. 1988). In fact, the peptide is most abundant in the heart and thus it is now commonly termed B-type natriuretic peptide (BNP). Myocyte pressure and/or stretch results in the release of BNP, and BNP levels are easily quantified by several commercially available assays. Data...

conclusions the results of the current study suggested that spinal anesthesia plus intravenous patient-controlled analgesia have the most favorable cardiac effects regarding postoperative levels of pro-bnp. results there was no difference between three groups for basic characteristics and variables and baseline pro-bnp levels; however, postoperative pro-bnp levels in groups a, b, and c were res...

Acute myocardial infarction (MI) results in activation of neurohormonal systems and increased plasma concentrations of myocardial enzymes and structural proteins. We hypothesized that plasma levels of N-terminal pro-brain natriuretic peptide (NT-BNP) would respond more vigorously after MI than those of other natriuretic peptides. We also sought to compare this response with that of the establis...

Brain natriuretic peptide (BNP) is a peptide hormone secreted by cardiomyocytes in response to atrial or ventricular wall stretch and/or pressure overload. It promotes a number of systemic effects, including vasodilatation, increase in urinary output and sodium excretion, as well as inhibition of the sympathetic nervous system and the renin–angiotensin–aldosterone system. Plasma BNP levels have...

The natriuretic peptide system consists of at least three endogenous ligands: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP), and three receptors, ANP-A receptor (guanylate cyclase A), ANP-B receptor (guanylate cyclase B) and clearance receptor (C receptor). ANP, the prototype of natriuretic peptides, is mainly produced in the atrium and s...

Background: Dilated cardiomyopathy (DCM) is revealed with the left ventricular dilatation and systolic dysfunction. This study was performed to determine the level of Calcitonin Gene Related Peptide (CGRP) and Brain Natriuretic Peptide (BNP) in children with dilated cardiomyopathy and controls and comparison of these two biomarkers in patients. Materials and Methods: This case-control study was...